STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEK22445.1Hypothetical protein; P-loop containing nucleoside triphosphate hydrolases (SSF52540); DUF889 (PF05970). (473 aa)    
Predicted Functional Partners:
AEK22443.1
Conserved hypothetical protein.
 
     0.742
AEK22444.1
Conserved hypothetical protein.
 
     0.709
AEK22806.1
Conserved hypothetical protein; N-terminus: SpI(LipoP); 2 transmembrane domains.
  
     0.675
AEK24360.1
Putative exodeoxyribonuclease V; Weak similarity to UniProt:Q033I1; Undefined Gene3D domain (G3DSA:3.40.50.300); P-loop containing nucleoside triphosphate hydrolases (SSF52540); DNA helicase, UvrD-like, C-terminal (PS51217); Helicase, superfamily 1, UvrD-related (PS51198); DNA helicase, UvrD/REP type (PF00580); DNA helicase, UvrD/REP type (PTHR11070); Protein involved in DNA binding, ATP-dependent DNA helicase activity, ATP binding, hydrolase activity and DNA repair.
 
 
 0.645
AEK22442.1
Putative rRNA methyltransferase ylbH; DNA methylase, N-6 adenine-specific, conserved site (PS00092); Conserved hypothetical protein CHP00095 (PF03602); METHYLTRANSFERASE (PTHR18895); Conserved hypothetical protein CHP00095 (PIRSF004553); Undefined Gene3D domain (G3DSA:3.40.50.150); S-adenosyl-L-methionine-dependent methyltransferases (SSF53335); Protein involved in nucleic acid binding, methyltransferase activity and methylation.
       0.583
AEK22882.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.548
purL
Formylglycinamide ribotide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
    0.497
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.449
AEK22190.1
Hypothetical protein; Weak similarity to UniProt:O34748; Undefined Gene3D domain (G3DSA:3.40.50.300); P-loop containing nucleoside triphosphate hydrolases (SSF52540); DNA/RNA helicase, C-terminal (PF00271); DNA HELICASE RECQ (PTHR13710:SF11); DNA/RNA helicase, DEAD/DEAH box type, N-terminal (PF00270); Helicase, superfamily 1/2, ATP-binding domain (PS51192); DEAD-like helicase, N-terminal (SM00487); DNA helicase, ATP-dependent, RecQ type (PTHR13710); DUF559 (PF04480); DNA/RNA helicase, C-terminal (PS51194); DNA/RNA helicase, C-terminal (SM00490); Protein involved in ATP-dependent helica [...]
  
 
 0.426
AEK22761.1
ATP-dependent DNA helicase pcrA; Undefined Gene3D domain (G3DSA:3.40.50.300); P-loop containing nucleoside triphosphate hydrolases (SSF52540); DNA helicase, UvrD-like, C-terminal (PS51217); Helicase, superfamily 1, UvrD-related (PS51198); DNA helicase, UvrD/REP type (PF00580); DNA helicase, UvrD/REP type (PTHR11070); Protein involved in ATP binding, hydrolase activity, DNA binding, ATP-dependent DNA helicase activity and DNA repair.
  
 
 0.422
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
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