| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEK22456.1 | AEK22458.1 | Ccan_03340 | Ccan_03360 | Pre-uroporphyrinogen synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Regulatory protein pchR; Helix-turn-helix, AraC type (PF00165); Helix-turn-helix, AraC domain (PS01124); ARAC FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN (PTHR11019:SF11); Helix-turn-helix, AraC domain (SM00342); Helix-turn-helix, AraC type, subdomain 2 (PS00041); Homeodomain-like (SSF46689); THIJ/PFPI (PTHR11019); Helix-turn-helix, AraC (PR00032); Protein involved in transcription factor activity, sequence-specific DNA binding and regulation of transcription, DNA-dependent. | 0.550 |
| AEK22456.1 | hemA | Ccan_03340 | Ccan_03350 | Pre-uroporphyrinogen synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.993 |
| AEK22458.1 | AEK22456.1 | Ccan_03360 | Ccan_03340 | Regulatory protein pchR; Helix-turn-helix, AraC type (PF00165); Helix-turn-helix, AraC domain (PS01124); ARAC FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN (PTHR11019:SF11); Helix-turn-helix, AraC domain (SM00342); Helix-turn-helix, AraC type, subdomain 2 (PS00041); Homeodomain-like (SSF46689); THIJ/PFPI (PTHR11019); Helix-turn-helix, AraC (PR00032); Protein involved in transcription factor activity, sequence-specific DNA binding and regulation of transcription, DNA-dependent. | Pre-uroporphyrinogen synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.550 |
| AEK22458.1 | AEK22459.1 | Ccan_03360 | Ccan_03370 | Regulatory protein pchR; Helix-turn-helix, AraC type (PF00165); Helix-turn-helix, AraC domain (PS01124); ARAC FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN (PTHR11019:SF11); Helix-turn-helix, AraC domain (SM00342); Helix-turn-helix, AraC type, subdomain 2 (PS00041); Homeodomain-like (SSF46689); THIJ/PFPI (PTHR11019); Helix-turn-helix, AraC (PR00032); Protein involved in transcription factor activity, sequence-specific DNA binding and regulation of transcription, DNA-dependent. | Hypothetical protein; Weak similarity to UniProt:P76578; N-terminus: SpII(LipoP); Undefined Gene3D domain (G3DSA:1.50.10.20); A2M (PF00207); Alpha-2-macroglobulin, thiol-ester bond-forming (PF10569); Terpenoid cylases/protein prenyltransferase alpha-alpha toroid (SSF48239); Alpha-2-macroglobulin, N-terminal (PF01835); Alpha-2-macroglobulin MG1 domain (PF11974); Alpha-2-macroglobulin, N-terminal 2 (PF07703); Protein involved in endopeptidase inhibitor activity. | 0.523 |
| AEK22458.1 | AEK22889.1 | Ccan_03360 | Ccan_07710 | Regulatory protein pchR; Helix-turn-helix, AraC type (PF00165); Helix-turn-helix, AraC domain (PS01124); ARAC FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN (PTHR11019:SF11); Helix-turn-helix, AraC domain (SM00342); Helix-turn-helix, AraC type, subdomain 2 (PS00041); Homeodomain-like (SSF46689); THIJ/PFPI (PTHR11019); Helix-turn-helix, AraC (PR00032); Protein involved in transcription factor activity, sequence-specific DNA binding and regulation of transcription, DNA-dependent. | Conserved hypothetical protein; N-terminus: SpI(LipoP). | 0.449 |
| AEK22458.1 | AEK23225.1 | Ccan_03360 | Ccan_11090 | Regulatory protein pchR; Helix-turn-helix, AraC type (PF00165); Helix-turn-helix, AraC domain (PS01124); ARAC FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN (PTHR11019:SF11); Helix-turn-helix, AraC domain (SM00342); Helix-turn-helix, AraC type, subdomain 2 (PS00041); Homeodomain-like (SSF46689); THIJ/PFPI (PTHR11019); Helix-turn-helix, AraC (PR00032); Protein involved in transcription factor activity, sequence-specific DNA binding and regulation of transcription, DNA-dependent. | Peptidyl-prolyl cis-trans isomerase; N-terminus: SpII(LipoP); 1 transmembrane domain; Peptidyl-prolyl cis-trans isomerase, FKBP-type (PS50059); Gliding motility-associated, peptidyl-prolyl isomerase, GldI (TIGR03516); Peptidyl-prolyl cis-trans isomerase, FKBP-type (PTHR10516); Undefined Gene3D domain (G3DSA:3.10.50.40); Peptidyl-prolyl cis-trans isomerase, FKBP-type (PF00254); FKBP-like (SSF54534); Protein involved in protein folding. | 0.560 |
| AEK22458.1 | AEK23262.1 | Ccan_03360 | Ccan_11460 | Regulatory protein pchR; Helix-turn-helix, AraC type (PF00165); Helix-turn-helix, AraC domain (PS01124); ARAC FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN (PTHR11019:SF11); Helix-turn-helix, AraC domain (SM00342); Helix-turn-helix, AraC type, subdomain 2 (PS00041); Homeodomain-like (SSF46689); THIJ/PFPI (PTHR11019); Helix-turn-helix, AraC (PR00032); Protein involved in transcription factor activity, sequence-specific DNA binding and regulation of transcription, DNA-dependent. | Secreted protein; N-terminus: SpI(LipoP). | 0.483 |
| AEK22458.1 | AEK23479.1 | Ccan_03360 | Ccan_13630 | Regulatory protein pchR; Helix-turn-helix, AraC type (PF00165); Helix-turn-helix, AraC domain (PS01124); ARAC FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN (PTHR11019:SF11); Helix-turn-helix, AraC domain (SM00342); Helix-turn-helix, AraC type, subdomain 2 (PS00041); Homeodomain-like (SSF46689); THIJ/PFPI (PTHR11019); Helix-turn-helix, AraC (PR00032); Protein involved in transcription factor activity, sequence-specific DNA binding and regulation of transcription, DNA-dependent. | Secreted protein; N-terminus: SpI(LipoP); Flags: Precursor. | 0.457 |
| AEK22458.1 | AEK24158.1 | Ccan_03360 | Ccan_20420 | Regulatory protein pchR; Helix-turn-helix, AraC type (PF00165); Helix-turn-helix, AraC domain (PS01124); ARAC FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN (PTHR11019:SF11); Helix-turn-helix, AraC domain (SM00342); Helix-turn-helix, AraC type, subdomain 2 (PS00041); Homeodomain-like (SSF46689); THIJ/PFPI (PTHR11019); Helix-turn-helix, AraC (PR00032); Protein involved in transcription factor activity, sequence-specific DNA binding and regulation of transcription, DNA-dependent. | Hypothetical protein; Weak similarity to UniProt:P28809; Homeodomain-related (G3DSA:1.10.10.60); ARAC FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN (PTHR11019:SF11); Homeodomain-like (SSF46689); Helix-turn-helix, AraC type (PF00165); Helix-turn-helix, AraC domain (PS01124); Helix-turn-helix, AraC domain (SM00342); Helix-turn-helix, AraC type, subdomain 2 (PS00041); THIJ/PFPI (PTHR11019); Helix-turn-helix, AraC (PR00032); Protein involved in DNA binding, transcription factor activity, sequence-specific DNA binding, regulation of transcription and regulation of transcription, DNA-dependent. | 0.590 |
| AEK22458.1 | AEK24212.1 | Ccan_03360 | Ccan_20960 | Regulatory protein pchR; Helix-turn-helix, AraC type (PF00165); Helix-turn-helix, AraC domain (PS01124); ARAC FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN (PTHR11019:SF11); Helix-turn-helix, AraC domain (SM00342); Helix-turn-helix, AraC type, subdomain 2 (PS00041); Homeodomain-like (SSF46689); THIJ/PFPI (PTHR11019); Helix-turn-helix, AraC (PR00032); Protein involved in transcription factor activity, sequence-specific DNA binding and regulation of transcription, DNA-dependent. | S-adenosyl-methyltransferase MraW. | 0.466 |
| AEK22458.1 | hemA | Ccan_03360 | Ccan_03350 | Regulatory protein pchR; Helix-turn-helix, AraC type (PF00165); Helix-turn-helix, AraC domain (PS01124); ARAC FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN (PTHR11019:SF11); Helix-turn-helix, AraC domain (SM00342); Helix-turn-helix, AraC type, subdomain 2 (PS00041); Homeodomain-like (SSF46689); THIJ/PFPI (PTHR11019); Helix-turn-helix, AraC (PR00032); Protein involved in transcription factor activity, sequence-specific DNA binding and regulation of transcription, DNA-dependent. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.572 |
| AEK22458.1 | rpoA | Ccan_03360 | Ccan_04670 | Regulatory protein pchR; Helix-turn-helix, AraC type (PF00165); Helix-turn-helix, AraC domain (PS01124); ARAC FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN (PTHR11019:SF11); Helix-turn-helix, AraC domain (SM00342); Helix-turn-helix, AraC type, subdomain 2 (PS00041); Homeodomain-like (SSF46689); THIJ/PFPI (PTHR11019); Helix-turn-helix, AraC (PR00032); Protein involved in transcription factor activity, sequence-specific DNA binding and regulation of transcription, DNA-dependent. | RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.517 |
| AEK22459.1 | AEK22458.1 | Ccan_03370 | Ccan_03360 | Hypothetical protein; Weak similarity to UniProt:P76578; N-terminus: SpII(LipoP); Undefined Gene3D domain (G3DSA:1.50.10.20); A2M (PF00207); Alpha-2-macroglobulin, thiol-ester bond-forming (PF10569); Terpenoid cylases/protein prenyltransferase alpha-alpha toroid (SSF48239); Alpha-2-macroglobulin, N-terminal (PF01835); Alpha-2-macroglobulin MG1 domain (PF11974); Alpha-2-macroglobulin, N-terminal 2 (PF07703); Protein involved in endopeptidase inhibitor activity. | Regulatory protein pchR; Helix-turn-helix, AraC type (PF00165); Helix-turn-helix, AraC domain (PS01124); ARAC FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN (PTHR11019:SF11); Helix-turn-helix, AraC domain (SM00342); Helix-turn-helix, AraC type, subdomain 2 (PS00041); Homeodomain-like (SSF46689); THIJ/PFPI (PTHR11019); Helix-turn-helix, AraC (PR00032); Protein involved in transcription factor activity, sequence-specific DNA binding and regulation of transcription, DNA-dependent. | 0.523 |
| AEK22889.1 | AEK22458.1 | Ccan_07710 | Ccan_03360 | Conserved hypothetical protein; N-terminus: SpI(LipoP). | Regulatory protein pchR; Helix-turn-helix, AraC type (PF00165); Helix-turn-helix, AraC domain (PS01124); ARAC FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN (PTHR11019:SF11); Helix-turn-helix, AraC domain (SM00342); Helix-turn-helix, AraC type, subdomain 2 (PS00041); Homeodomain-like (SSF46689); THIJ/PFPI (PTHR11019); Helix-turn-helix, AraC (PR00032); Protein involved in transcription factor activity, sequence-specific DNA binding and regulation of transcription, DNA-dependent. | 0.449 |
| AEK22889.1 | AEK23225.1 | Ccan_07710 | Ccan_11090 | Conserved hypothetical protein; N-terminus: SpI(LipoP). | Peptidyl-prolyl cis-trans isomerase; N-terminus: SpII(LipoP); 1 transmembrane domain; Peptidyl-prolyl cis-trans isomerase, FKBP-type (PS50059); Gliding motility-associated, peptidyl-prolyl isomerase, GldI (TIGR03516); Peptidyl-prolyl cis-trans isomerase, FKBP-type (PTHR10516); Undefined Gene3D domain (G3DSA:3.10.50.40); Peptidyl-prolyl cis-trans isomerase, FKBP-type (PF00254); FKBP-like (SSF54534); Protein involved in protein folding. | 0.695 |
| AEK22889.1 | AEK23262.1 | Ccan_07710 | Ccan_11460 | Conserved hypothetical protein; N-terminus: SpI(LipoP). | Secreted protein; N-terminus: SpI(LipoP). | 0.772 |
| AEK22889.1 | AEK23479.1 | Ccan_07710 | Ccan_13630 | Conserved hypothetical protein; N-terminus: SpI(LipoP). | Secreted protein; N-terminus: SpI(LipoP); Flags: Precursor. | 0.769 |
| AEK22889.1 | AEK24212.1 | Ccan_07710 | Ccan_20960 | Conserved hypothetical protein; N-terminus: SpI(LipoP). | S-adenosyl-methyltransferase MraW. | 0.751 |
| AEK23225.1 | AEK22458.1 | Ccan_11090 | Ccan_03360 | Peptidyl-prolyl cis-trans isomerase; N-terminus: SpII(LipoP); 1 transmembrane domain; Peptidyl-prolyl cis-trans isomerase, FKBP-type (PS50059); Gliding motility-associated, peptidyl-prolyl isomerase, GldI (TIGR03516); Peptidyl-prolyl cis-trans isomerase, FKBP-type (PTHR10516); Undefined Gene3D domain (G3DSA:3.10.50.40); Peptidyl-prolyl cis-trans isomerase, FKBP-type (PF00254); FKBP-like (SSF54534); Protein involved in protein folding. | Regulatory protein pchR; Helix-turn-helix, AraC type (PF00165); Helix-turn-helix, AraC domain (PS01124); ARAC FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN (PTHR11019:SF11); Helix-turn-helix, AraC domain (SM00342); Helix-turn-helix, AraC type, subdomain 2 (PS00041); Homeodomain-like (SSF46689); THIJ/PFPI (PTHR11019); Helix-turn-helix, AraC (PR00032); Protein involved in transcription factor activity, sequence-specific DNA binding and regulation of transcription, DNA-dependent. | 0.560 |
| AEK23225.1 | AEK22889.1 | Ccan_11090 | Ccan_07710 | Peptidyl-prolyl cis-trans isomerase; N-terminus: SpII(LipoP); 1 transmembrane domain; Peptidyl-prolyl cis-trans isomerase, FKBP-type (PS50059); Gliding motility-associated, peptidyl-prolyl isomerase, GldI (TIGR03516); Peptidyl-prolyl cis-trans isomerase, FKBP-type (PTHR10516); Undefined Gene3D domain (G3DSA:3.10.50.40); Peptidyl-prolyl cis-trans isomerase, FKBP-type (PF00254); FKBP-like (SSF54534); Protein involved in protein folding. | Conserved hypothetical protein; N-terminus: SpI(LipoP). | 0.695 |