STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmkGMP kinase; Essential for recycling GMP and indirectly, cGMP. (190 aa)    
Predicted Functional Partners:
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
 
 
 0.964
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.961
AEK22559.1
UPF0701 protein yloC; Guanine nucleotide binding protein (G-protein), alpha subunit (PTHR10218); GUANINE NUCLEOTIDE-BINDING PROTEIN G(F), ALPHA SUBUNIT (PTHR10218:SF29); Domain of unknown function DUF1732 (PF08340); YicC-like, N-terminal (PF03755); Protein involved in signal transducer activity, guanyl nucleotide binding and G-protein coupled receptor protein signaling pathway.
  
    0.930
AEK22539.1
Short=NDK;Short=NDP kinase;AltName: Full=Nucleoside-2-P kinase; Nucleoside diphosphate kinase, core (PR01243); Nucleoside diphosphate kinase, core (G3DSA:3.30.70.141); Nucleoside diphosphate kinase, core (SSF54919); Nucleoside diphosphate kinase, core (PTHR11349); Nucleoside diphosphate kinase, core (SM00562); Nucleoside diphosphate kinase, core (PS00469); Nucleoside diphosphate kinase, core (PF00334); Protein involved in nucleoside diphosphate kinase activity, ATP binding, GTP biosynthetic process, UTP biosynthetic process and CTP biosynthetic process.
   
 0.926
AEK23296.1
(p)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.920
AEK22395.1
Short=PK; Pyruvate kinase, alpha/beta (PF02887); Pyruvate/Phosphoenolpyruvate kinase, catalytic core (G3DSA:3.20.20.60); Pyruvate kinase (TIGR01064); Pyruvate kinase, beta-barrel-like (SSF50800); Pyruvate kinase, barrel (PR01050); Pyruvate/Phosphoenolpyruvate kinase, catalytic core (SSF51621); Pyruvate kinase, barrel (PF00224); Pyruvate kinase (PTHR11817); Pyruvate kinase, C-terminal-like (SSF52935); Pyruvate kinase, active site (PS00110); Pyruvate kinase, alpha/beta (G3DSA:3.40.1380.20); Protein involved in catalytic activity, magnesium ion binding, pyruvate kinase activity, potassium [...]
  
 
 0.918
surE
Nucleoside 5'-monophosphate phosphohydrolase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
  
  
  0.917
AEK22597.1
Short=DGUO kinase;Short=dGK; P-loop containing nucleoside triphosphate hydrolases (SSF52540); Undefined Gene3D domain (G3DSA:3.40.50.300); Deoxynucleoside kinase (PTHR10513); Deoxynucleoside kinase (PF01712); 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK (G3DSA:3.30.70.560); 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK (SSF55083); 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK (TIGR01498); 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK (PF01288); DEOXYGUANOSINE KINASE/DEOXYADENOSINE KINASE (PTHR10513:SF3); Protein involved in 2-amino-4-hyd [...]
     
 0.914
AEK23265.1
AltName: Full=Ribonucleotide reductase large subunit; Ribonucleotide reductase large subunit, C-terminal (PF02867); PFL-like glycyl radical enzymes (SSF51998); Undefined Gene3D domain (G3DSA:3.90.244.10); Ribonucleoside-diphosphate reductase alpha chain (TIGR02510); Ribonucleotide reductase large subunit, C-terminal (PTHR11573); Ribonucleotide reductase large subunit, C-terminal (PR01183); Protein involved in ribonucleoside-diphosphate reductase activity and DNA replication.
     
 0.912
AEK23059.1
Conserved hypothetical protein; RNA polymerase Rpb6 (PF01192); Protein involved in DNA binding, DNA-directed RNA polymerase activity and transcription, DNA-dependent.
  
  
 0.905
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
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