STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoARNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (330 aa)    
Predicted Functional Partners:
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
 
 0.999
rpsM
30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.
 
 0.998
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
 
 
 0.998
rpoC
RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 0.997
rpoB
RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 0.997
AEK23059.1
Conserved hypothetical protein; RNA polymerase Rpb6 (PF01192); Protein involved in DNA binding, DNA-directed RNA polymerase activity and transcription, DNA-dependent.
 
 0.995
rpsC
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
 
 
 0.994
AEK22578.1
Ribosomal protein S8 (PTHR11758); Undefined Gene3D domain (G3DSA:3.30.1370.30); Ribosomal protein S8 (SSF56047); Ribosomal protein S8 (PF00410); Undefined Gene3D domain (G3DSA:3.30.1490.10); Ribosomal protein S8 (PS00053); Protein involved in structural constituent of ribosome and translation; Belongs to the universal ribosomal protein uS8 family.
 
 
 0.993
rpsE
30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
 
 
 0.992
rplQ
Ribosomal protein L17 (MF_01368); Ribosomal protein L17 (G3DSA:3.90.1030.10); RIBOSOMAL PROTEIN L17 (PTHR14413:SF3); Ribosomal protein L17 (PF01196); Ribosomal protein L17 (PS01167); Ribosomal protein L17 (TIGR00059); Ribosomal protein L17 (PTHR14413); Ribosomal protein L17 (SSF64263); Protein involved in structural constituent of ribosome and translation.
 
 
 0.990
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
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