STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
carAN-terminus: SpI(LipoP); AltName: Full=Carbamoyl-phosphate synthetase glutamine chain; Carbamoyl phosphate synthase, GATase domain (PR00099); Glutamine amidotransferase class-I, C-terminal (PF00117); Class I glutamine amidotransferase-like (SSF52317); Carbamoyl phosphate synthase, small subunit, N-terminal (PF00988); CARBAMOYLTRANSFERASE RELATED (PTHR11405); Undefined Gene3D domain (G3DSA:3.40.50.880); Anthranilate synthase component II/delta crystallin (PR00097); Glutamine amidotransferase superfamily (PR00096); Carbamoyl phosphate synthase, small subunit, N-terminal (SSF52021); Glutam [...] (367 aa)    
Predicted Functional Partners:
AEK22745.1
N-terminus: SpII(ProfileScan); AltName: Full=Carbamoyl-phosphate synthetase ammonia chain; 1 transmembrane domain; Undefined Gene3D domain (G3DSA:1.10.1030.10); Carbamoyl phosphate synthase, large subunit, N-terminal (PF00289); PreATP-grasp-like fold (SSF52440); Carbamoyl phosphate synthetase, large subunit, ATP-binding (PF02786); CARBAMOYLTRANSFERASE RELATED (PTHR11405); ATP-grasp fold (PS50975); Carbamoyl phosphate synthetase, large subunit, ATP-binding (PS00867); Carbamoyl phosphate synthetase, large subunit, oligomerisation (PF02787); Carbamoyl phosphate synthetase, large subunit, [...]
 0.999
pyrB
AltName: Full=Aspartate transcarbamylase;Short=ATCase; Undefined Gene3D domain (G3DSA:3.40.50.1370); Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding (PF02729); Aspartate carbamoyltransferase, eukaryotic (TIGR00670); CARBAMOYLTRANSFERASE RELATED (PTHR11405); Aspartate carbamoyltransferase, eukaryotic (MF_00001); Aspartate/ornithine carbamoyltransferase (SSF53671); Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain (PF00185); Aspartate/ornithine carbamoyltransferase (PS00097); Aspartate/ornithine carbamoyltransferase (PR00100); Aspartate carbamoyltransferase, [...]
 
 0.999
AEK22435.1
Dihydroorotase; Short=DHOase; Metal-dependent hydrolase, composite domain (SSF51338); Dihydroorotase, conserved site (PS00483); Metallo-dependent hydrolases (SSF51556); AMINOHYDROLASE (PTHR11647); Undefined Gene3D domain (G3DSA:3.20.20.140); DIHYDROOROTASE (PTHR11647:SF5); Amidohydrolase 1 (PF01979); Protein involved in hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides, hydrolase activity and hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds.
  
 0.974
AEK22278.1
Short=ATase;AltName: Full=Glutamine phosphoribosylpyrophosphate amidotransferase;Short=GPATase; N-terminal nucleophile aminohydrolases (Ntn hydrolases) (SSF56235); Undefined Gene3D domain (G3DSA:3.60.20.10); PRTase-like (SSF53271); Glutamine amidotransferase, type II (PS51278); Glutamine amidotransferase, class-II (PF00310); Amidophosphoribosyl transferase (PTHR11907); Protein involved in amidophosphoribosyltransferase activity, purine base biosynthetic process and metabolic process.
  
 
 0.953
purL
Formylglycinamide ribotide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.939
pyrD
DHOdehase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
  
 0.915
AEK22771.1
Short=GS;AltName: Full=Glutamate--ammonia ligase; Glutamine synthetase, catalytic domain (PF00120); Glutamine synthetase type III N-terminal (PF12437); GLUTAMINE SYNTHETASE-BACTERIA (PTHR20852:SF5); Glutamine synthetase, catalytic domain (PS00181); Glutamine synthetase/guanido kinase (SSF55931); GLUTAMINE SYNTHETASE (PTHR20852); Glutamine synthetase/guanido kinase, catalytic domain (G3DSA:3.30.590.10); Protein involved in glutamate-ammonia ligase activity, catalytic activity and nitrogen compound metabolic process.
  
 
  0.908
AEK22961.1
AltName: Full=OMP decarboxylase;Short=OMPDCase;Short=OMPdecase; Ribulose-phosphate binding barrel (SSF51366); Aldolase-type TIM barrel (G3DSA:3.20.20.70); Orotidine 5'-phosphate decarboxylase, subfamily 2, core (TIGR02127); Orotidine 5'-phosphate decarboxylase, core (PF00215); Protein involved in orotidine-5'-phosphate decarboxylase activity, catalytic activity, pyrimidine nucleotide biosynthetic process, metabolic process and 'de novo' pyrimidine base biosynthetic process.
  
  
 0.887
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.886
AEK23150.1
Dihydroorotase; Short=DHOase; Metallo-dependent hydrolases (SSF51556); Metal-dependent hydrolase, composite domain (SSF51338); DIHYDROOROTASE (PTHR11647:SF2); AMINOHYDROLASE (PTHR11647); Undefined Gene3D domain (G3DSA:3.20.20.140); Protein involved in hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds.
 
  
 0.763
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
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