STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEK22596.1Signal peptide peptidase; N-terminus: SpI(LipoP); AltName: Full=Protease IV homolog;AltName: Full=Endopeptidase IV;AltName: Full=Signal peptide peptidase; 1 transmembrane domain; Peptidase S49, SppA (TIGR00706); Undefined Gene3D domain (G3DSA:3.90.226.10); Peptidase S49 (PF01343); Peptidase S49, protease IV (TIGR00705); ClpP/crotonase (SSF52096); Peptidase S49, protease IV (PIRSF001217); Protein involved in peptidase activity, signal peptide processing and proteolysis. (587 aa)    
Predicted Functional Partners:
AEK22597.1
Short=DGUO kinase;Short=dGK; P-loop containing nucleoside triphosphate hydrolases (SSF52540); Undefined Gene3D domain (G3DSA:3.40.50.300); Deoxynucleoside kinase (PTHR10513); Deoxynucleoside kinase (PF01712); 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK (G3DSA:3.30.70.560); 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK (SSF55083); 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK (TIGR01498); 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK (PF01288); DEOXYGUANOSINE KINASE/DEOXYADENOSINE KINASE (PTHR10513:SF3); Protein involved in 2-amino-4-hyd [...]
       0.614
AEK22598.1
Hydroxymethylbilane hydrolyase (cyclizing); Includes:RecName: Full=Uroporphyrinogen-III C-methyltransferase;Short=Urogen III methylase;AltName: Full=SUMT;AltName: Full=Uroporphyrinogen III methylase;Short=UROM;Includes:RecName: Full=Uroporphyrinogen-III synthase;Short=UROS;AltName: Full=Uroporphyrinogen-III cosynthetase;AltName: Full=Hydroxymethylbilane hydrolyase [cyclizing]; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase (SSF69618); Tetrapyrrole biosynthesis, uroporphyrinogen III synthase (PF02602); Undefined Gene3D domain (G3DSA:3.40.50.10090); UROPORPHYRINOGEN III SYNTHAS [...]
       0.546
AEK22322.1
Aspartate kinase 2; AltName: Full=Aspartokinase II;AltName: Full=Aspartate kinase 2.
  
    0.504
AEK22514.1
Conserved hypothetical protein; N-terminus: SpI(LipoP); Flags: Precursor; 1 transmembrane domain; Immunoglobulin (SSF48726).
  
    0.489
secF
Protein-export membrane protein secD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
   
 0.482
AEK24068.1
AltName: Full=Aspartokinase I/homoserine dehydrogenase I;Short=AKI-HDI;Includes:RecName: Full=Aspartokinase;Includes:RecName: Full=Homoserine dehydrogenase; Aspartate/glutamate/uridylate kinase (SSF53633); NAD(P)-binding domain (G3DSA:3.40.50.720); Homoserine dehydrogenase, conserved site (PS01042); Amino acid-binding ACT (PF01842); Homoserine dehydrogenase, catalytic (PF00742); Aspartate/glutamate/uridylate kinase (G3DSA:3.40.1160.10); Bifunctional aspartokinase/homoserine dehydrogenase I (PIRSF000727); Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (SSF55347); Aspar [...]
 
     0.476
mscL
Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
     
 0.449
AEK22513.1
Conserved hypothetical protein; N-terminus: SpI(SignalPHMM); DUF3308 (PF11751); Conserved hypothetical protein CHP03519, membrane, Bacteroidetes (TIGR03519); Sporulation related domain (PF05036).
  
     0.432
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
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