STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panBKetopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (287 aa)    
Predicted Functional Partners:
panC
Pantoate-activating enzyme; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 0.996
ilvD
Short=DAD; Dihydroxy-acid dehydratase (MF_00012); Dihydroxy-acid/6-phosphogluconate dehydratase (PTHR21000); Dihydroxy-acid/6-phosphogluconate dehydratase (PF00920); Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site (PS00886); Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site (PS00887); Dihydroxy-acid dehydratase (TIGR00110); Protein involved in catalytic activity, dihydroxy-acid dehydratase activity, metabolic process and branched chain family amino acid biosynthetic process; Belongs to the IlvD/Edd family.
     
 0.927
panD
Aspartate 1-decarboxylase alpha chain; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
  
 0.914
AEK24107.1
Vegetative protein 85; Surface exposed; Short=BCAT 2;AltName: Full=Vegetative protein 85;Short=VEG85; Branched-chain amino acid aminotransferase II (TIGR01123); Branched-chain amino acid aminotransferase II (PIRSF006468); Aminotransferase, class IV (PF01063); Branched-chain amino acid aminotransferase II (PTHR11825:SF2); Aminotransferase, class IV, conserved site (PS00770); Aminotransferase, class IV (SSF56752); Undefined Gene3D domain (G3DSA:3.30.470.10); Aminotransferase, class IV (PTHR11825); Undefined Gene3D domain (G3DSA:3.20.10.10); Protein involved in branched-chain-amino-acid t [...]
    
 0.912
AEK22755.1
RNA pseudouridylate synthase; AltName: Full=RNA-uridine isomerase;AltName: Full=RNA pseudouridylate synthase; RIBOSOMAL PSEUDOURIDINE SYNTHASE (PTHR10436); Pseudouridine synthase, RluC/RluD, conserved site (PS01129); Pseudouridine synthase, RsuA and RluB/C/D/E/F (PF00849); Pseudouridine synthase, catalytic domain (SSF55120); Protein involved in RNA binding, pseudouridine synthase activity, pseudouridine synthesis and RNA modification.
       0.714
AEK22752.1
Conserved hypothetical protein.
       0.693
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
     
 0.616
AEK22754.1
N-terminus: TMH(LipoP); 6 transmembrane domains; Protein of unknown function DUF1275 (PF06912).
       0.592
AEK23717.1
HTP reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.550
AEK22751.1
70 kDa antigen; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
       0.498
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
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