STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEK22887.1Transcriptional regulatory protein zraR; P-loop containing nucleoside triphosphate hydrolases (SSF52540); Undefined Gene3D domain (G3DSA:3.40.50.300); Signal transduction response regulator, receiver domain (PF00072); TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE REGULATOR (INTESTINAL BACTERIA - BACTEROIDES THETAIOTAOMICRON) (PTHR23283:SF21); Signal transduction response regulator, receiver domain (SM00448); RNA polymerase sigma factor 54, interaction (PS00676); ATPase, AAA+ type, core (SM00382); CheY-like (SSF52172); RNA polymerase sigma factor 54, interaction (PF00158); Undef [...] (387 aa)    
Predicted Functional Partners:
AEK24179.1
Putative sensor histidine kinase ntrY-like protein; N-terminus: SpI(LipoP); 2 transmembrane domains; Signal transduction histidine kinase, homodimeric (SSF47384); ATPase-like, ATP-binding domain (SSF55874); Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain (SM00388); TWO COMPONENT HISTIDINE KINASE (SPORULATION KINASE) (PTHR23283:SF24); ATPase-like, ATP-binding domain (PF02518); ATPase-like, ATP-binding domain (G3DSA:3.30.565.10); HAMP linker domain (PF00672); Signal transduction histidine kinase, core (PS50109); ATPase-like, ATP-binding domain (SM003 [...]
 
 0.966
AEK24079.1
RNA polymerase sigma factor 54 (PS50044); RNA polymerase sigma factor 54, DNA-binding (PF04552); RNA polymerase sigma factor 54, core-binding (PF04963); RNA polymerase sigma factor 54 (PS00718); RNA polymerase sigma factor 54 (PF00309); RNA polymerase sigma factor 54 (TIGR02395); RNA polymerase sigma factor 54 (PR00045); Protein involved in DNA binding, transcription factor activity, DNA-directed RNA polymerase activity, sigma factor activity, transcription initiation and regulation of transcription, DNA-dependent.
 
  
 0.788
AEK22886.1
Protein sanA; N-terminus: TMH(LipoP); 1 transmembrane domain; Protein of unknown function DUF218 (PF02698).
       0.773
AEK23644.1
Sensor protein evgS; N-terminus: TMH(LipoP); Flags: Precursor; 3 transmembrane domains; Signal transduction histidine kinase, homodimeric (SSF47384); ATPase-like, ATP-binding domain (SSF55874); TETRACYCLINE RESISTANCE ELEMENT REGULATOR RTEA - BACTEROIDES THETAIOTAOMICRON (PTHR23283:SF38); Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain (SM00388); Signal transduction histidine kinase, phosphotransfer (Hpt) domain (SSF47226); Undefined Gene3D domain (G3DSA:1.10.287.240); ATPase-like, ATP-binding domain (PF02518); Signal transduction histidine kinase, [...]
  
 
 0.728
AEK22884.1
Hypothetical protein; Weak similarity to UniProt:O51693; N-terminus: SpI(SignalPHMM); 2 transmembrane domains; Gliding-associated putative ABC transporter substrate-binding GldG (TIGR03521); ABC-type uncharacterised transport system (PF09822).
       0.723
AEK22885.1
Hypothetical protein; Weak similarity to UniProt:P0AFQ0; N-terminus: TMH(LipoP); 6 transmembrane domains.
       0.723
AEK24250.1
Autoinducer 2 sensor kinase/phosphatase luxQ; N-terminus: SpII(ProfileScan); 1 transmembrane domain; Signal transduction histidine kinase, homodimeric (SSF47384); ATPase-like, ATP-binding domain (SSF55874); Tetratricopeptide repeat (SM00028); Homeodomain-related (G3DSA:1.10.10.60); Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain (SM00388); Undefined Gene3D domain (G3DSA:1.10.287.240); ATPase-like, ATP-binding domain (PF02518); Signal transduction response regulator, receiver domain (PF00072); Tetratricopeptide-like helical (G3DSA:1.25.40.10); HCP-l [...]
  
 
0.505
AEK22882.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
       0.504
AEK22888.1
N-terminus: TMH(LipoP); 12 transmembrane domains; Protein of unknown function DUF819 (PF05684).
       0.493
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
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