STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEK23039.1Acyl-activating enzyme; AltName: Full=Acetate--CoA ligase;AltName: Full=Acyl-activating enzyme; ATP-DEPENDENT AMP-BINDING ENZYME FAMILY MEMBER (PTHR11968); Acetyl-CoA synthetase-like (SSF56801); Undefined Gene3D domain (G3DSA:3.30.300.30); Acetate--CoA (TIGR02188); AMP-binding (PR00154); Undefined Gene3D domain (G3DSA:2.30.38.10); DUF3448 (PF11930); AMP-dependent synthetase/ligase (PF00501); ACETYL-COENZYME A SYNTHETASE (ACETATE--COA LIGASE) (PTHR11968:SF42); AMP-binding, conserved site (PS00455); Undefined Gene3D domain (G3DSA:3.40.50.980); Protein involved in acetate-CoA ligase activ [...] (1278 aa)    
Predicted Functional Partners:
AEK23466.1
Citrate synthase-like, core (SSF48256); Citrate synthase-like (PR00143); Citrate synthase, type II (TIGR01798); Citrate synthase active site (PS00480); Citrate synthase-like, large alpha subdomain (G3DSA:1.10.580.10); Citrate synthase-like (PTHR11739); Citrate synthase-like (PF00285); Protein involved in transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer, citrate (Si)-synthase activity, cellular carbohydrate metabolic process and tricarboxylic acid cycle.
  
 0.979
AEK23576.1
Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.945
AEK23037.1
M2 antigen complex 70 kDa subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.942
ackA
Acetokinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.940
AEK22340.1
Acetyl-CoA carboxylase subunit A; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.925
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
    
 0.918
AEK22339.1
Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
    
 0.906
accA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
    
 0.906
sucC
Succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.886
pdhA
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.886
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
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