STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
AEK23089.1Phosphatidylserine synthase; N-terminus: TMH(LipoP); AltName: Full=Phosphatidylserine synthase; 7 transmembrane domains; CDP-alcohol phosphatidyltransferase (PF01066); CDP-alcohol phosphatidyltransferase (PS00379); Protein involved in phosphotransferase activity, for other substituted phosphate groups and phospholipid biosynthetic process; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (237 aa)    
Predicted Functional Partners:
AEK22849.1
N-terminus: TMH(LipoP); Contains:RecName: Full=Phosphatidylserine decarboxylase alpha chain;Contains:RecName: Full=Phosphatidylserine decarboxylase beta chain; 2 transmembrane domains; Phosphatidylserine decarboxylase-related protein (TIGR00164); Phosphatidylserine decarboxylase-related (PF02666); Protein involved in phosphatidylserine decarboxylase activity, cofactor binding, phosphatidylethanolamine biosynthetic process and phospholipid biosynthetic process.
 
 
 0.983
AEK22848.1
CDP-DAG synthase; N-terminus: TMH(LipoP); AltName: Full=CDP-diglyceride pyrophosphorylase;AltName: Full=CDP-diglyceride synthase;AltName: Full=CDP-diacylglycerol synthase;Short=CDS;AltName: Full=CTP:phosphatidate cytidylyltransferase;AltName: Full=CDP-DG synthase;AltName: Full=CDP-DAG synthase; 8 transmembrane domains; Phosphatidate cytidylyltransferase (PF01148); PHOSPHATIDATE CYTIDYLYLTRANSFERASE (PTHR13773); Phosphatidate cytidylyltransferase (PS01315); Protein involved in transferase activity, transferring phosphorus-containing groups; Belongs to the CDS family.
    
 0.931
AEK23118.1
Beta-thionase; AltName: Full=Serine sulfhydrase;AltName: Full=Beta-thionase; BRCT (SM00292); Undefined Gene3D domain (G3DSA:3.40.50.1100); Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site (PS00901); CYSTEINE SYNTHASE (PTHR10314:SF8); SER/THR DEHYDRATASE, TRP SYNTHASE (PTHR10314); Pyridoxal phosphate-dependent enzyme, beta subunit (SSF53686); Pyridoxal phosphate-dependent enzyme, beta subunit (PF00291); Protein involved in catalytic activity, pyridoxal phosphate binding, cysteine biosynthetic process from serine and metabolic process.
   
 
 0.902
AEK22652.1
Short=SDH;AltName: Full=L-serine deaminase;Short=L-SD; Iron-sulphur-dependent L-serine dehydratase single chain form (TIGR00720); Serine dehydratase beta chain (PF03315); Serine dehydratase-like, alpha subunit (PF03313); Protein involved in L-serine ammonia-lyase activity, 4 iron, 4 sulfur cluster binding and gluconeogenesis; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.900
ilvA
Threonine deaminase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
    
  0.900
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
  0.900
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
  0.900
AEK23905.1
N-terminus: SpI(LipoP); AltName: Full=Phosphatidylcholine 1-acylhydrolase;Flags: Precursor; Phospholipase A1 (G3DSA:2.40.230.10); Phospholipase A1 (PF02253); Phospholipase A1 (SSF56931); Phospholipase A1 (PR01486); Protein involved in phospholipase activity and lipid metabolic process.
     
  0.900
AEK24069.1
N-terminus: TMH(LipoP); AltName: Full=Homoserine O-trans-acetylase;Short=Homoserine transacetylase;Short=HTA; 1 transmembrane domain; Alpha/beta hydrolase fold-1 (PF00561); alpha/beta-Hydrolases (SSF53474).
     
  0.800
AEK23088.1
Rotamase; Surface exposed; N-terminus: SpII(LipoP); Short=PPIase;AltName: Full=Rotamase;Flags: Precursor; Peptidyl-prolyl cis-trans isomerase, FKBP-type (PS50059); Peptidyl-prolyl cis-trans isomerase, FKBP-type (PTHR10516); Undefined Gene3D domain (G3DSA:3.10.50.40); FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE (PTHR10516:SF17); FKBP-like (SSF54534); Protein involved in protein folding.
  
    0.591
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
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