STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEK23155.1Short=AE epimerase;Short=AEE;EC=5.1.1.n1; Mandelate racemase/muconate lactonizing enzyme, C-terminal (PF01188); Undefined Gene3D domain (G3DSA:3.20.20.120); Enolase C-terminal domain-like (SSF51604); Mandelate racemase/muconate lactonizing enzyme, conserved site (PS00909); Enolase N-terminal domain-like (SSF54826); MUCONATE CYCLOISOMERASE (PTHR13794:SF7); Mandelate racemase/muconate lactonizing enzyme (PTHR13794); Protein involved in catalytic activity, metabolic process and cellular amino acid catabolic process. (356 aa)    
Predicted Functional Partners:
AEK23448.1
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II-like protein; ATP-DEPENDENT AMP-BINDING ENZYME FAMILY MEMBER (PTHR11968); Acetyl-CoA synthetase-like (SSF56801); Beta tubulin, autoregulation binding site (PS00228); Undefined Gene3D domain (G3DSA:3.30.300.30); AMP-dependent synthetase/ligase (PF00501); Undefined Gene3D domain (G3DSA:3.40.50.980); O-SUCCINYLBENZOIC ACID--COA LIGASE (PTHR11968:SF14); Protein involved in catalytic activity and metabolic process.
 
  0.993
menD
Menaquinone biosynthesis protein menD; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
   
 0.799
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
 
   
 0.720
AEK23156.1
DNA polymerase III subunit alpha; Polymerase/histidinol phosphatase-like (SSF89550); DNA (TIGR00594); Polynucleotidyl transferase, ribonuclease H fold (SSF53098); Exonuclease, RNase T/DNA polymerase III (PF00929); PHP, C-terminal (PF02811); Polymerase/histidinol phosphatase, N-terminal (SM00481); Bacterial DNA polymerase III, alpha subunit (PF07733); Nucleic acid-binding, OB-fold-like (SSF50249); Undefined Gene3D domain (G3DSA:3.30.420.10); Protein involved in DNA binding, DNA-directed DNA polymerase activity, 3'-5' exonuclease activity, nucleic acid binding, catalytic activity and DNA [...]
       0.709
AEK22808.1
AltName: Full=Isochorismate mutase; Chorismate binding, C-terminal (PF00425); ADC synthase (SSF56322); Isochorismate synthase (PTHR11236:SF3); Isochorismate synthase (TIGR00543); ADC synthase (PTHR11236); ADC synthase (G3DSA:3.60.120.10); Protein involved in isochorismate synthase activity and biosynthetic process.
 
   
 0.636
menB
Dihydroxynaphthoic acid synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
 
   
 0.610
AEK23157.1
Hypothetical protein; Weak similarity to UniProt:C9KR18.
       0.574
AEK22811.1
Conserved hypothetical protein; Protein of unknown function DUF1599 (PF07659).
  
     0.536
AEK24280.1
Hypothetical protein; Weak similarity to UniProt:Q8E5U0.
  
    0.488
AEK22264.1
Conserved hypothetical protein; Tetratricopeptide repeat (PS50005).
  
     0.473
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
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