STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEK23452.1Short=AspAT;AltName: Full=Transaminase A; SUBGROUP I AMINOTRANSFERASE RELATED (PTHR11751); Pyridoxal phosphate-dependent transferase, major domain (SSF53383); ASPARTATE AMINOTRANSFERASE (PTHR11751:SF35); Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (G3DSA:3.40.640.10); Aminotransferase, class I/II (PF00155); Protein involved in transferase activity, transferring nitrogenous groups, pyridoxal phosphate binding, catalytic activity and biosynthetic process. (417 aa)    
Predicted Functional Partners:
AEK24437.1
Gene duplicate 1-A/1-B protein; AltName: Full=Imidazole acetol-phosphate transaminase;AltName: Full=Gene duplicate 1-A/1-B protein;Flags: Precursor; SUBGROUP I AMINOTRANSFERASE RELATED (PTHR11751); Pyridoxal phosphate-dependent transferase, major domain (SSF53383); Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (G3DSA:3.40.640.10); HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (PTHR11751:SF3); Aminotransferase, class I/II (PF00155); Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (G3DSA:3.90.1150.10); Protein involved in catalytic activity, pyridoxal [...]
 
 
 0.926
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.923
AEK23960.1
Short=AspAT;AltName: Full=Transaminase A; SUBGROUP I AMINOTRANSFERASE RELATED (PTHR11751); Pyridoxal phosphate-dependent transferase, major domain (SSF53383); 1-aminocyclopropane-1-carboxylate synthase (PR00753); ASPARTATE AMINOTRANSFERASE (PTHR11751:SF35); Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (G3DSA:3.40.640.10); Aminotransferase, class I/II (PF00155); Aminotransferases, class-I, pyridoxal-phosphate-binding site (PS00105); Protein involved in catalytic activity, pyridoxal phosphate binding, transferase activity, transferring nitrogenous groups, 1-aminoc [...]
  
  
 
0.923
AEK22840.1
Short=P5C dehydrogenase;AltName: Full=Aldehyde dehydrogenase family 4 member A1 homolog;Flags: Precursor; Aldehyde dehydrogenase, N-terminal (G3DSA:3.40.605.10); Aldehyde dehydrogenase (PF00171); Delta-1-pyrroline-5-carboxylate dehydrogenase 1 (TIGR01236); Aldehyde dehydrogenase, conserved site (PS00070); Aldehyde dehydrogenase (PTHR11699); DELTA-1-PYROLINE-5-CARBOXYLATE DEHYDROGENASE (PTHR11699:SF18); Aldehyde/histidinol dehydrogenase (SSF53720); Aldehyde dehydrogenase, conserved site (PS00687); Protein involved in oxidoreductase activity, 1-pyrroline-5-carboxylate dehydrogenase activ [...]
   
 0.921
AEK23004.1
Cysteine lyase; Short=CBL;AltName: Full=Beta-cystathionase;AltName: Full=Cysteine lyase; SUBGROUP I AMINOTRANSFERASE RELATED (PTHR11751); Pyridoxal phosphate-dependent transferase, major domain (SSF53383); Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (G3DSA:3.40.640.10); Aminotransferase, class I/II (PF00155); AMINOTRANSFERASE RELATED (PTHR11751:SF21); Protein involved in catalytic activity, pyridoxal phosphate binding, transferase activity, transferring nitrogenous groups and biosynthetic process.
 
  
 0.920
AEK22772.1
Short=GDH; Glutamate/phenylalanine/leucine/valine dehydrogenase (PR00082); NAD(P)-binding domain (G3DSA:3.40.50.720); Aminoacid dehydrogenase-like, N-terminal domain (SSF53223); Glutamate/phenylalanine/leucine/valine dehydrogenase (PS00074); Glutamate dehydrogenase (PIRSF000185); Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain (PF02812); GLUTAMATE DEHYDROGENASE (PTHR11606); Undefined Gene3D domain (G3DSA:3.40.192.10); NAD(P)-binding domain (SSF51735); Glutamate/phenylalanine/leucine/valine dehydrogenase (PTHR11606:SF2); Glutamate/phenylalanine/leucine/valine d [...]
  
 
 0.914
purA
AMPSase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
   
 0.914
AEK22656.1
Prephenate dehydrogenase; N-terminus: SpI(SignalPHMM); AltName: Full=Cyclohexadienyl dehydrogenase;AltName: Full=Arogenate dehydrogenase;Short=ADH;AltName: Full=Prephenate dehydrogenase;Short=PDH; NAD(P)-binding domain (G3DSA:3.40.50.720); Prephenate dehydrogenase (PS51176); Prephenate dehydrogenase (PF02153); Prephenate dehydrogenase (PTHR21363); NAD(P)-binding domain (SSF51735); Protein involved in catalytic activity, binding, prephenate dehydrogenase (NADP+) activity, metabolic process and tyrosine biosynthetic process.
  
 
 0.913
AEK24068.1
AltName: Full=Aspartokinase I/homoserine dehydrogenase I;Short=AKI-HDI;Includes:RecName: Full=Aspartokinase;Includes:RecName: Full=Homoserine dehydrogenase; Aspartate/glutamate/uridylate kinase (SSF53633); NAD(P)-binding domain (G3DSA:3.40.50.720); Homoserine dehydrogenase, conserved site (PS01042); Amino acid-binding ACT (PF01842); Homoserine dehydrogenase, catalytic (PF00742); Aspartate/glutamate/uridylate kinase (G3DSA:3.40.1160.10); Bifunctional aspartokinase/homoserine dehydrogenase I (PIRSF000727); Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (SSF55347); Aspar [...]
  
 0.910
AEK22476.1
Aspartate ammonia-lyase; Short=Aspartase; L-Aspartase-like (SSF48557); Fumarate lyase, conserved site (PS00163); Fumarate lyase (PR00149); Undefined Gene3D domain (G3DSA:1.20.200.10); Undefined Gene3D domain (G3DSA:1.10.40.30); ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE (PTHR11444); ASPARTATE AMMONIA LYASE (PTHR11444:SF1); Fumarate lyase (PF00206); Aspartate ammonia-lyase (TIGR00839); Delta crystallin (PR00145); Undefined Gene3D domain (G3DSA:1.10.275.10); Fumarase C, C-terminal (PF10415); FUMC_MF_00743 (MF_00743); Protein involved in catalytic activity, aspartate ammoni [...]
     
 0.909
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.