STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEK23531.1Conserved hypothetical protein; N-terminus: TMH(LipoP); 4 transmembrane domains; Colicin V production protein (PF02674); Protein involved in toxin biosynthetic process. (173 aa)    
Predicted Functional Partners:
purL
Formylglycinamide ribotide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
   
  
 0.971
AEK22278.1
Short=ATase;AltName: Full=Glutamine phosphoribosylpyrophosphate amidotransferase;Short=GPATase; N-terminal nucleophile aminohydrolases (Ntn hydrolases) (SSF56235); Undefined Gene3D domain (G3DSA:3.60.20.10); PRTase-like (SSF53271); Glutamine amidotransferase, type II (PS51278); Glutamine amidotransferase, class-II (PF00310); Amidophosphoribosyl transferase (PTHR11907); Protein involved in amidophosphoribosyltransferase activity, purine base biosynthetic process and metabolic process.
  
  
 0.876
AEK23067.1
AltName: Full=AIRS;AltName: Full=Phosphoribosyl-aminoimidazole synthetase;AltName: Full=AIR synthase; PHOSPHORIBOSYLAMINE-GLYCINE LIGASE-RELATED (PTHR10520); Undefined Gene3D domain (G3DSA:3.30.1330.10); AIR synthase related protein, C-terminal (PF02769); gb def: Putative phosphoribosylformylglycinamidine cyclo-ligase (PTHR10520:SF4); PurM, N-terminal-like (SSF55326); AIR synthase related protein, C-terminal (SSF56042); Undefined Gene3D domain (G3DSA:3.90.650.10); Protein involved in catalytic activity.
   
    0.768
purC
AltName: Full=SAICAR synthetase; SAICAR synthetase (PF01259); SAICAR synthetase (MF_00137); Undefined Gene3D domain (G3DSA:3.30.200.20); PURINE BIOSYNTHESIS PROTEIN 7, PUR7 (PTHR11609:SF1); SAICAR synthetase, conserved site (PS01058); SAICAR synthetase (PTHR11609); ATP-grasp fold, subdomain 2 (G3DSA:3.30.470.20); SAICAR synthase-like (SSF56104); Protein involved in phosphoribosylaminoimidazolesuccinocarboxamide synthase activity, catalytic activity, ATP binding and purine nucleotide biosynthetic process.
  
    0.740
purE
AIR carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
   
    0.671
AEK23532.1
N-terminus: TMH(LipoP); 8 transmembrane domains; Protein of unknown function DUF81 (PF01925).
       0.572
AEK23561.1
Conserved hypothetical protein; Cell division protein ZapA-like (PF05164); Cell division protein ZapA-like (SSF102829).
 
  
 0.566
AEK22378.1
Conserved hypothetical protein; N-terminus: SpII(LipoP); 1 transmembrane domain; Lipopolysccharide-assembly, LptC-related (PF06835).
 
    0.514
purH
atiC; Includes:RecName: Full=Phosphoribosylaminoimidazolecarboxamide formyltransferase;AltName: Full=AICAR transformylase;Includes:RecName: Full=IMP cyclohydrolase;AltName: Full=Inosinicase;AltName: Full=IMP synthetase;AltName: Full=ATIC; Undefined Gene3D domain (G3DSA:3.40.50.1380); AICARFT/IMPCHase bienzyme (PIRSF000414); Undefined Gene3D domain (G3DSA:3.40.140.20); MGS-like (PF02142); AICARFT/IMPCHase bienzyme (TIGR00355); AICARFT/IMPCHase bienzyme, transformylase domain (SSF64197); Methylglyoxal synthase-like (SSF52335); AICARFT/IMPCHase bienzyme (PTHR11692); AICARFT/IMPCHase bienz [...]
   
    0.508
purN
GAR transformylase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
   
  
 0.501
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.