STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEK23701.1AltName: Full=Long-chain acyl-CoA synthetase;Short=LACS; Acetyl-CoA synthetase-like (SSF56801); ATP-DEPENDENT AMP-BINDING ENZYME FAMILY MEMBER (PTHR11968); AMP-binding (PR00154); Undefined Gene3D domain (G3DSA:2.30.38.10); AMP-dependent synthetase/ligase (PF00501); LONG-CHAIN-FATTY-ACID COA LIGASE (PTHR11968:SF10); AMP-binding, conserved site (PS00455); Undefined Gene3D domain (G3DSA:3.40.50.980); Protein involved in catalytic activity and metabolic process. (597 aa)    
Predicted Functional Partners:
AEK24161.1
AltName: Full=Long-chain acyl-CoA synthetase;Short=LACS; Acetyl-CoA synthetase-like (SSF56801); ATP-DEPENDENT AMP-BINDING ENZYME FAMILY MEMBER (PTHR11968); AMP-binding (PR00154); Undefined Gene3D domain (G3DSA:2.30.38.10); AMP-dependent synthetase/ligase (PF00501); LONG-CHAIN-FATTY-ACID COA LIGASE (PTHR11968:SF10); Undefined Gene3D domain (G3DSA:3.40.50.980); Protein involved in catalytic activity and metabolic process.
  
  
 
0.915
AEK22430.1
ACYL-COA DEHYDROGENASE (PTHR10909:SF10); Acyl-CoA oxidase/dehydrogenase, central domain (PF02770); ELECTRON TRANSPORT OXIDOREDUCTASE (PTHR10909); Acyl-CoA dehydrogenase/oxidase, N-terminal (G3DSA:1.10.540.10); Acyl-CoA dehydrogenase, conserved site (PS00073); Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal (G3DSA:1.20.140.10); Acyl-CoA dehydrogenase/oxidase (SSF56645); Acyl-CoA oxidase/dehydrogenase, central domain (G3DSA:2.40.110.10); Acyl-CoA oxidase/dehydrogenase, type 1 (PF00441); Acyl-CoA dehydrogenase, N-terminal (PF02771); Acyl-CoA dehydrogenase/oxidase C-terminal (SSF47203) [...]
  
 0.680
AEK23702.1
Short=Ferric uptake regulator; Ferric-uptake regulator (PF01475); Winged helix DNA-binding domain (SSF46785); Protein involved in transcription factor activity and regulation of transcription, DNA-dependent; Belongs to the Fur family.
       0.623
purA
AMPSase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
       0.623
bioD
DTB synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
       0.504
rplE
50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
    
 
 0.495
gmk
GMP kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.471
AEK23699.1
Conserved hypothetical protein; N-terminus: SpI(LipoP); 1 transmembrane domain.
       0.430
AEK23698.1
Alpha-oxoamine synthase; Short=AONS/AKB ligase;AltName: Full=8-amino-7-ketopelargonate synthase;AltName: Full=7-keto-8-amino-pelargonic acid synthase;Short=KAPA synthase;Short=7-KAP synthase;AltName: Full=L-alanine--pimeloyl-CoA ligase;AltName: Full=Alpha-oxoamine synthase; CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE (PTHR13693); Pyridoxal phosphate-dependent transferase, major domain (SSF53383); Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (G3DSA:3.40.640.10); Aminotransferase, class I/II (PF00155); Aminotransferase, class-II, pyridoxal-phosphate [...]
   
 
 0.423
rplR
50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
    
 
 0.408
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
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