STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (284 aa)    
Predicted Functional Partners:
accA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 0.999
AEK22339.1
Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.998
AEK22340.1
Acetyl-CoA carboxylase subunit A; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 0.997
AEK23517.1
Malonyl CoA-acyl carrier protein transacylase; Locus: Belongs to PUL_7; Short=MCT; Acyl transferase domain (G3DSA:3.40.366.10); MALONYL COA-ACYL CARRIER PROTEIN TRANSACYLASE (PTHR10982:SF4); Malonyl CoA-acyl carrier protein transacylase (TIGR00128); Malonyl-CoA ACP transacylase, ACP-binding (SSF55048); MALONYL COENZYME A-ACYL CARRIER PROTEIN TRANSACYLASE-RELATED (PTHR10982); Acyl transferase (PF00698); Acyl transferase/acyl hydrolase/lysophospholipase (SSF52151); Protein involved in catalytic activity, binding, transferase activity, [acyl-carrier-protein] S-malonyltransferase activity, [...]
 
 
 0.979
fabH
Beta-ketoacyl-ACP synthase III 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.968
AEK23209.1
AltName: Full=3-oxoacyl-[acyl-carrier-protein] synthase III;AltName: Full=Beta-ketoacyl-ACP synthase III;Short=KAS III; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal (PF08541); 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III (PF08545); Thiolase-like (SSF53901); Thiolase-like, subgroup (G3DSA:3.40.47.10); Protein involved in catalytic activity, transferase activity, transferring acyl groups other than amino-acyl groups, 3-oxoacyl-[acyl-carrier-protein] synthase activity, metabolic process, lipid biosynthetic process and fatty acid biosynthetic process.
 
 
 0.968
fabH-2
Beta-ketoacyl-ACP synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.967
fabZ
(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
 
  
 0.925
AEK23039.1
Acyl-activating enzyme; AltName: Full=Acetate--CoA ligase;AltName: Full=Acyl-activating enzyme; ATP-DEPENDENT AMP-BINDING ENZYME FAMILY MEMBER (PTHR11968); Acetyl-CoA synthetase-like (SSF56801); Undefined Gene3D domain (G3DSA:3.30.300.30); Acetate--CoA (TIGR02188); AMP-binding (PR00154); Undefined Gene3D domain (G3DSA:2.30.38.10); DUF3448 (PF11930); AMP-dependent synthetase/ligase (PF00501); ACETYL-COENZYME A SYNTHETASE (ACETATE--COA LIGASE) (PTHR11968:SF42); AMP-binding, conserved site (PS00455); Undefined Gene3D domain (G3DSA:3.40.50.980); Protein involved in acetate-CoA ligase activ [...]
    
 0.918
AEK23576.1
Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.916
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.