STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
truBtRNA pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (250 aa)    
Predicted Functional Partners:
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
 
 0.935
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.923
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
  
  
 0.901
AEK23525.1
FAD synthetase; Locus: Belongs to PUL_7; Includes:RecName: Full=Riboflavin kinase;AltName: Full=Flavokinase;Includes:RecName: Full=FMN adenylyltransferase;AltName: Full=FAD pyrophosphorylase;AltName: Full=FAD synthetase; Riboflavin kinase (PF01687); Riboflavin kinase/FAD synthetase (PIRSF004491); Rossmann-like alpha/beta/alpha sandwich fold (G3DSA:3.40.50.620); Riboflavin kinase (PTHR22749); FAD synthetase (PF06574); Riboflavin kinase/FAD synthetase (TIGR00083); Riboflavin kinase (G3DSA:2.40.30.30); Riboflavin kinase (SSF82114); Nucleotidylyl transferase (SSF52374); Protein involved in [...]
 
  
 0.825
AEK23815.1
tRNA pseudouridine synthase B; N-terminus: SpI(LipoP); 1 transmembrane domain.
       0.806
AEK22751.1
70 kDa antigen; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
 
 
 0.792
nusA
Transcription elongation protein nusA; Participates in both transcription termination and antitermination.
  
    0.781
trmB
tRNA(m7G46)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
 
 0.750
rpsO
30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
  
 
 0.732
rpoC
RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.725
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
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