STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AEK24001.1Single-stranded-DNA-specific exonuclease recJ; Phosphoesterase, DHHA1 (PF02272); Phosphoesterase, RecJ-like (PF01368); Bacterial RecJ exonuclease (TIGR00644); DHH phosphoesterases (SSF64182); Protein involved in 5'-3' exonuclease activity, hydrolase activity, manganese ion binding, nucleic acid binding, DNA repair and DNA recombination. (563 aa)    
Predicted Functional Partners:
AEK24002.1
Protein yhfA; K homology-like, alpha/beta (G3DSA:3.30.300.20); Peroxiredoxin, OsmC-like protein (SSF82784); Peroxiredoxin, OsmC-like protein (PF02566); Protein involved in response to stress.
       0.724
AEK22249.1
Short=SSB;AltName: Full=Helix-destabilizing protein; Nucleic acid-binding, OB-fold (G3DSA:2.40.50.140); Primosome PriB/single-strand DNA-binding (PS50935); Single-strand DNA-binding (TIGR00621); Single-strand DNA-binding (PTHR10302); Primosome PriB/single-strand DNA-binding (PF00436); Nucleic acid-binding, OB-fold-like (SSF50249); Protein involved in single-stranded DNA binding and DNA replication.
  
 
 0.669
AEK24000.1
N-terminus: SpI(SignalPHMM); AltName: Full=Mucoidy activation protein mucZ; TerB (PF05099); DNAJ-RELATED (PTHR11821:SF71); Heat shock protein DnaJ, N-terminal (SM00271); Heat shock protein DnaJ, N-terminal (SSF46565); Heat shock protein DnaJ, N-terminal (PF00226); Heat shock protein DnaJ, N-terminal (PS50076); Heat shock protein DnaJ, N-terminal (G3DSA:1.10.287.110); Molecular chaperone, heat shock protein, Hsp40, DnaJ (PTHR11821); Protein involved in heat shock protein binding.
  
    0.583
priA
Replication factor Y; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
 
     0.582
AEK23201.1
ATP-dependent DNA helicase recQ; P-loop containing nucleoside triphosphate hydrolases (SSF52540); Undefined Gene3D domain (G3DSA:3.40.50.300); DNA helicase, ATP-dependent, RecQ type, N-terminal (TIGR00614); Helicase, superfamily 1/2, ATP-binding domain (PS51192); DNA/RNA helicase, DEAD/DEAH box type, N-terminal (PF00270); DNA helicase, ATP-dependent, RecQ type (PTHR13710); DNA/RNA helicase, C-terminal (PS51194); DNA HELICASE RECQ (PTHR13710:SF11); DNA/RNA helicase, C-terminal (PF00271); DEAD-like helicase, N-terminal (SM00487); DNA/RNA helicase, C-terminal (SM00490); Protein involved i [...]
    
 0.564
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
   
 0.562
secF
Protein-export membrane protein secD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
     
 0.554
murE
UDP-MurNAc-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
  
 0.510
ruvC
Holliday junction resolvase ruvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
 
 
 
 0.497
AEK24003.1
Hypothetical protein; 1 transmembrane domain.
       0.492
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
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