STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdxJPyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (237 aa)    
Predicted Functional Partners:
pdxH
Pyridoxal 5'-phosphate synthase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
     
 0.927
AEK22400.1
AltName: Full=4-(phosphohydroxy)-L-threonine dehydrogenase; Isocitrate/Isopropylmalate dehydrogenase-like (SSF53659); Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA (TIGR00557); Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA (PF04166); Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA (MF_00536); Protein involved in 4-hydroxythreonine-4-phosphate dehydrogenase activity, NAD or NADH binding, pyridoxine biosynthetic process and oxidation reduction; Belongs to the PdxA family.
 
 
 0.915
AEK24043.1
AltName: Full=Williams-Beuren syndrome chromosomal region 21 protein homolog; ABHYDROLASE (PR00111); Alpha/beta hydrolase fold-1 (PF00561); alpha/beta-Hydrolases (SSF53474); VALACYCLOVIR HYDROLASE (PTHR10992:SF17); ALPHA/BETA HYDROLASE RELATED (PTHR10992); Undefined Gene3D domain (G3DSA:3.40.50.1820).
       0.846
AEK24042.1
Hypothetical protein; N-terminus: TMH(LipoP); 4 transmembrane domains; Membrane protein of unknown function (PF04020).
       0.672
AEK24041.1
Conserved putative Non-specific serine/threonine protein kinase; Enzymatic activity prediction (EC) from PRIAM_profiles_2090616; N-terminus: SpI(LipoP); 1 transmembrane domain; Penicillin-binding protein 2x (pbp-2x), c-terminal domain (SSF54184); PASTA (SM00740); PASTA (PS51178); PASTA (PF03793); Protein involved in penicillin binding.
       0.615
dxs
1-deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.578
ribB
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
 0.548
AEK24045.1
Thioredoxin family protein; N-terminus: SpII(LipoP); Thioredoxin, core (PTHR10438); Thioredoxin fold (G3DSA:3.40.30.10); Thioredoxin-like (PS51352); Redoxin (PF08534); Thioredoxin-like fold (SSF52833); Protein involved in oxidoreductase activity and cell redox homeostasis.
   
   0.539
AEK24040.1
RNA pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
 
    0.527
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
 
   
 0.519
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.