| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEK22829.1 | AEK24247.1 | Ccan_07090 | Ccan_21310 | AltName: Full=Murein peptide ligase; Mur ligase, N-terminal (PF01225); NAD(P)-binding domain (G3DSA:3.40.50.720); MurCD N-terminal domain (SSF51984); Mur ligase, C-terminal (G3DSA:3.90.190.20); Mur ligase, C-terminal (SSF53244); Mur ligase, central (SSF53623); Mur ligase, central (G3DSA:3.40.1190.10); UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE (PTHR23135:SF5); Mur ligase, central (PF08245); MUR LIGASE FAMILY MEMBER (PTHR23135); Protein involved in ATP binding, catalytic activity, binding, ligase activity, biosynthetic process and metabolic process. | Cell division protein FtsQ; N-terminus: SpI(LipoP); 1 transmembrane domain. | 0.690 |
| AEK22829.1 | ddl | Ccan_07090 | Ccan_13860 | AltName: Full=Murein peptide ligase; Mur ligase, N-terminal (PF01225); NAD(P)-binding domain (G3DSA:3.40.50.720); MurCD N-terminal domain (SSF51984); Mur ligase, C-terminal (G3DSA:3.90.190.20); Mur ligase, C-terminal (SSF53244); Mur ligase, central (SSF53623); Mur ligase, central (G3DSA:3.40.1190.10); UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE (PTHR23135:SF5); Mur ligase, central (PF08245); MUR LIGASE FAMILY MEMBER (PTHR23135); Protein involved in ATP binding, catalytic activity, binding, ligase activity, biosynthetic process and metabolic process. | D-Ala-D-Ala ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.604 |
| AEK22829.1 | murA | Ccan_07090 | Ccan_13300 | AltName: Full=Murein peptide ligase; Mur ligase, N-terminal (PF01225); NAD(P)-binding domain (G3DSA:3.40.50.720); MurCD N-terminal domain (SSF51984); Mur ligase, C-terminal (G3DSA:3.90.190.20); Mur ligase, C-terminal (SSF53244); Mur ligase, central (SSF53623); Mur ligase, central (G3DSA:3.40.1190.10); UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE (PTHR23135:SF5); Mur ligase, central (PF08245); MUR LIGASE FAMILY MEMBER (PTHR23135); Protein involved in ATP binding, catalytic activity, binding, ligase activity, biosynthetic process and metabolic process. | UDP-N-acetylglucosamine enolpyruvyl transferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.616 |
| AEK22829.1 | murB | Ccan_07090 | Ccan_19300 | AltName: Full=Murein peptide ligase; Mur ligase, N-terminal (PF01225); NAD(P)-binding domain (G3DSA:3.40.50.720); MurCD N-terminal domain (SSF51984); Mur ligase, C-terminal (G3DSA:3.90.190.20); Mur ligase, C-terminal (SSF53244); Mur ligase, central (SSF53623); Mur ligase, central (G3DSA:3.40.1190.10); UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE (PTHR23135:SF5); Mur ligase, central (PF08245); MUR LIGASE FAMILY MEMBER (PTHR23135); Protein involved in ATP binding, catalytic activity, binding, ligase activity, biosynthetic process and metabolic process. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.681 |
| AEK22829.1 | murE | Ccan_07090 | Ccan_21200 | AltName: Full=Murein peptide ligase; Mur ligase, N-terminal (PF01225); NAD(P)-binding domain (G3DSA:3.40.50.720); MurCD N-terminal domain (SSF51984); Mur ligase, C-terminal (G3DSA:3.90.190.20); Mur ligase, C-terminal (SSF53244); Mur ligase, central (SSF53623); Mur ligase, central (G3DSA:3.40.1190.10); UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE (PTHR23135:SF5); Mur ligase, central (PF08245); MUR LIGASE FAMILY MEMBER (PTHR23135); Protein involved in ATP binding, catalytic activity, binding, ligase activity, biosynthetic process and metabolic process. | UDP-MurNAc-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.569 |
| AEK22829.1 | murF | Ccan_07090 | Ccan_02820 | AltName: Full=Murein peptide ligase; Mur ligase, N-terminal (PF01225); NAD(P)-binding domain (G3DSA:3.40.50.720); MurCD N-terminal domain (SSF51984); Mur ligase, C-terminal (G3DSA:3.90.190.20); Mur ligase, C-terminal (SSF53244); Mur ligase, central (SSF53623); Mur ligase, central (G3DSA:3.40.1190.10); UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE (PTHR23135:SF5); Mur ligase, central (PF08245); MUR LIGASE FAMILY MEMBER (PTHR23135); Protein involved in ATP binding, catalytic activity, binding, ligase activity, biosynthetic process and metabolic process. | D-alanyl-D-alanine-adding enzyme; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.775 |
| AEK22829.1 | murG | Ccan_07090 | Ccan_21270 | AltName: Full=Murein peptide ligase; Mur ligase, N-terminal (PF01225); NAD(P)-binding domain (G3DSA:3.40.50.720); MurCD N-terminal domain (SSF51984); Mur ligase, C-terminal (G3DSA:3.90.190.20); Mur ligase, C-terminal (SSF53244); Mur ligase, central (SSF53623); Mur ligase, central (G3DSA:3.40.1190.10); UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE (PTHR23135:SF5); Mur ligase, central (PF08245); MUR LIGASE FAMILY MEMBER (PTHR23135); Protein involved in ATP binding, catalytic activity, binding, ligase activity, biosynthetic process and metabolic process. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.781 |
| AEK24045.1 | murB | Ccan_19290 | Ccan_19300 | Thioredoxin family protein; N-terminus: SpII(LipoP); Thioredoxin, core (PTHR10438); Thioredoxin fold (G3DSA:3.40.30.10); Thioredoxin-like (PS51352); Redoxin (PF08534); Thioredoxin-like fold (SSF52833); Protein involved in oxidoreductase activity and cell redox homeostasis. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.723 |
| AEK24247.1 | AEK22829.1 | Ccan_21310 | Ccan_07090 | Cell division protein FtsQ; N-terminus: SpI(LipoP); 1 transmembrane domain. | AltName: Full=Murein peptide ligase; Mur ligase, N-terminal (PF01225); NAD(P)-binding domain (G3DSA:3.40.50.720); MurCD N-terminal domain (SSF51984); Mur ligase, C-terminal (G3DSA:3.90.190.20); Mur ligase, C-terminal (SSF53244); Mur ligase, central (SSF53623); Mur ligase, central (G3DSA:3.40.1190.10); UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE (PTHR23135:SF5); Mur ligase, central (PF08245); MUR LIGASE FAMILY MEMBER (PTHR23135); Protein involved in ATP binding, catalytic activity, binding, ligase activity, biosynthetic process and metabolic process. | 0.690 |
| AEK24247.1 | ddl | Ccan_21310 | Ccan_13860 | Cell division protein FtsQ; N-terminus: SpI(LipoP); 1 transmembrane domain. | D-Ala-D-Ala ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.758 |
| AEK24247.1 | murB | Ccan_21310 | Ccan_19300 | Cell division protein FtsQ; N-terminus: SpI(LipoP); 1 transmembrane domain. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.632 |
| AEK24247.1 | murC | Ccan_21310 | Ccan_21300 | Cell division protein FtsQ; N-terminus: SpI(LipoP); 1 transmembrane domain. | UDP-N-acetylmuramoyl-L-alanine synthetase; Cell wall formation; Belongs to the MurCDEF family. | 0.982 |
| AEK24247.1 | murE | Ccan_21310 | Ccan_21200 | Cell division protein FtsQ; N-terminus: SpI(LipoP); 1 transmembrane domain. | UDP-MurNAc-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.704 |
| AEK24247.1 | murF | Ccan_21310 | Ccan_02820 | Cell division protein FtsQ; N-terminus: SpI(LipoP); 1 transmembrane domain. | D-alanyl-D-alanine-adding enzyme; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.723 |
| AEK24247.1 | murG | Ccan_21310 | Ccan_21270 | Cell division protein FtsQ; N-terminus: SpI(LipoP); 1 transmembrane domain. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.956 |
| ddl | AEK22829.1 | Ccan_13860 | Ccan_07090 | D-Ala-D-Ala ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | AltName: Full=Murein peptide ligase; Mur ligase, N-terminal (PF01225); NAD(P)-binding domain (G3DSA:3.40.50.720); MurCD N-terminal domain (SSF51984); Mur ligase, C-terminal (G3DSA:3.90.190.20); Mur ligase, C-terminal (SSF53244); Mur ligase, central (SSF53623); Mur ligase, central (G3DSA:3.40.1190.10); UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE (PTHR23135:SF5); Mur ligase, central (PF08245); MUR LIGASE FAMILY MEMBER (PTHR23135); Protein involved in ATP binding, catalytic activity, binding, ligase activity, biosynthetic process and metabolic process. | 0.604 |
| ddl | AEK24247.1 | Ccan_13860 | Ccan_21310 | D-Ala-D-Ala ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Cell division protein FtsQ; N-terminus: SpI(LipoP); 1 transmembrane domain. | 0.758 |
| ddl | murA | Ccan_13860 | Ccan_13300 | D-Ala-D-Ala ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylglucosamine enolpyruvyl transferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.736 |
| ddl | murB | Ccan_13860 | Ccan_19300 | D-Ala-D-Ala ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.641 |
| ddl | murC | Ccan_13860 | Ccan_21300 | D-Ala-D-Ala ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-L-alanine synthetase; Cell wall formation; Belongs to the MurCDEF family. | 0.979 |