STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEK24528.1O-6-methylguanine-DNA-alkyltransferase; AltName: Full=6-O-methylguanine-DNA methyltransferase;Short=MGMT;AltName: Full=O-6-methylguanine-DNA-alkyltransferase; Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding (PTHR10815); Methylguanine DNA methyltransferase, ribonuclease-like (PF02870); Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding (SSF46767); Methylated DNA-protein cysteine methyltransferase domain (SSF53155); Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding (PF01035); Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA bi [...] (173 aa)    
Predicted Functional Partners:
AEK23078.1
Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
      0.670
AEK24526.1
AltName: Full=Ap4A hydrolase;AltName: Full=Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase;Short=Diadenosine tetraphosphatase; Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (PTHR11668); PROTEIN PHOSPHATASE, CAEEL (PTHR11668:SF16); Metallo-dependent phosphatases (SSF56300); Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (PR00114); Undefined Gene3D domain (G3DSA:3.60.21.10); Metallophosphoesterase (PF00149); Protein involved in hydrolase activity.
  
  
 0.572
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.571
AEK24527.1
Conserved hypothetical protein; ATPase, AAA-4 (PF04326); Protein involved in ATP binding.
       0.533
AEK22453.1
Hypothetical protein; UspA (PF00582); Adenine nucleotide alpha hydrolases-like (SSF52402); Rossmann-like alpha/beta/alpha sandwich fold (G3DSA:3.40.50.620); Universal stress protein A (PR01438); Protein involved in response to stress.
  
    0.495
AEK23745.1
Hypothetical protein; THREE PRIME REPAIR EXONUCLEASE 2 (PTHR13058:SF5); Excinuclease ABC, C subunit, N-terminal (SM00465); Excinuclease ABC, C subunit, N-terminal (SSF82771); Polynucleotidyl transferase, ribonuclease H fold (SSF53098); Exonuclease, RNase T/DNA polymerase III (PF00929); DNA polymerase III, epsilon subunit (TIGR00573); Excinuclease ABC, C subunit, N-terminal (PF01541); Excinuclease ABC, C subunit, N-terminal (PS50164); THREE PRIME REPAIR EXONUCLEASE 1, 2 (PTHR13058); Exonuclease (SM00479); Undefined Gene3D domain (G3DSA:3.30.420.10); Protein involved in nuclease activity [...]
     
 0.450
AEK23237.1
Sigma-43; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   0.404
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.