ALG08349.1 protein (Kibdelosporangium phytohabitans)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

ALG08349.1

Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)

Predicted Functional Partners:

ALG08350.1

0.979

ALG14840.1

0.952

ALG08352.1

0.899

ALG10561.1

0.870

ALG11811.1

0.861

ALG08351.1

0.859

ALG11810.1

0.859

ALG08348.1

0.846

ALG10637.1

0.842

ALG11808.1

0.794

Your Current Organism:

Kibdelosporangium phytohabitans

NCBI taxonomy Id: 860235
Other names: CCTCC AA 2010001, K. phytohabitans, KCTC 19775, Kibdelosporangium phytohabitans Xing et al. 2012

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALG08348.1	ALG08349.1	AOZ06_16800	AOZ06_16805	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.846
ALG08348.1	ALG08350.1	AOZ06_16800	AOZ06_16815	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.979
ALG08348.1	ALG08351.1	AOZ06_16800	AOZ06_16820	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.889
ALG08348.1	ALG08352.1	AOZ06_16800	AOZ06_16825	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Response regulator receiver protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.923
ALG08348.1	ALG10561.1	AOZ06_16800	AOZ06_29975	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.870
ALG08348.1	ALG10637.1	AOZ06_16800	AOZ06_30410	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.845
ALG08348.1	ALG11810.1	AOZ06_16800	AOZ06_37455	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.878
ALG08348.1	ALG11811.1	AOZ06_16800	AOZ06_37460	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.861
ALG08348.1	ALG14840.1	AOZ06_16800	AOZ06_16810	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Anti-sigma regulatory factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.958
ALG08349.1	ALG08348.1	AOZ06_16805	AOZ06_16800	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.846
ALG08349.1	ALG08350.1	AOZ06_16805	AOZ06_16815	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.979
ALG08349.1	ALG08351.1	AOZ06_16805	AOZ06_16820	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.859
ALG08349.1	ALG08352.1	AOZ06_16805	AOZ06_16825	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Response regulator receiver protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.899
ALG08349.1	ALG10561.1	AOZ06_16805	AOZ06_29975	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.870
ALG08349.1	ALG10637.1	AOZ06_16805	AOZ06_30410	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.842
ALG08349.1	ALG11808.1	AOZ06_16805	AOZ06_37445	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.794
ALG08349.1	ALG11810.1	AOZ06_16805	AOZ06_37455	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.859
ALG08349.1	ALG11811.1	AOZ06_16805	AOZ06_37460	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.861
ALG08349.1	ALG14840.1	AOZ06_16805	AOZ06_16810	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Anti-sigma regulatory factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.952
ALG08350.1	ALG08348.1	AOZ06_16815	AOZ06_16800	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.979

page 1 of 6

Network Stats

number of nodes:

10

number of edges:

39

average node degree:

7.8

avg. local clustering coefficient:

0.95

expected number of edges:

12

PPI enrichment p-value:

8.87e-10

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006099

Tricarboxylic acid cycle

5 of 16

1.88

2.51

2.70e-06

GO:0045333

Cellular respiration

7 of 52

1.51

2.12

7.29e-07

GO:0006091

Generation of precursor metabolites and energy

8 of 110

1.25

1.6

7.46e-07

GO:0009141

Nucleoside triphosphate metabolic process

3 of 22

1.52

0.77

0.0255

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0045239

Tricarboxylic acid cycle enzyme complex

2 of 4

2.08

1.03

0.0116

GO:1990204

Oxidoreductase complex

3 of 19

1.58

0.94

0.0109

GO:1902494

Catalytic complex

4 of 71

1.14

0.74

0.0116

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1417

Citrate cycle (TCA cycle), and Glyoxylate cycle

5 of 23

1.72

2.1

1.25e-05

CL:1414

Mixed, incl. Citrate cycle (TCA cycle), and Branched-chain amino acid metabolic process

6 of 48

1.48

1.79

1.25e-05

CL:1418

Mixed, incl. Tricarboxylic acid cycle, and Pyruvate dehydrogenase complex

3 of 14

1.72

1.27

0.0022

CL:1229

Mixed, incl. Fatty acid metabolic process, and Citrate cycle (TCA cycle)

7 of 148

1.06

1.07

5.28e-05

CL:1446

Succinate dehydrogenase activity, and 4Fe-4S dicluster domain

2 of 7

1.84

0.78

0.0315

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00020

Citrate cycle (TCA cycle)

7 of 20

1.93

3.96

1.74e-10

map01200

Carbon metabolism

7 of 76

1.35

1.85

3.78e-07

map00190

Oxidative phosphorylation

4 of 48

1.31

1.12

0.0011

map00620

Pyruvate metabolism

3 of 34

1.33

0.9

0.0074

map01120

Microbial metabolism in diverse environments

7 of 222

0.88

0.78

0.00030

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0045274

Plasma membrane respiratory chain complex II

2 of 2

2.39

1.19

0.0064

GOCC:0045239

Tricarboxylic acid cycle enzyme complex

2 of 3

2.21

1.11

0.0084

GOCC:1990204

Oxidoreductase complex

4 of 35

1.44

1.09

0.0028

GOCC:1902494

Catalytic complex

6 of 144

1.01

0.78

0.0028

GOCC:0098796

Membrane protein complex

4 of 106

0.96

0.56

0.0281

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0816

Tricarboxylic acid cycle

3 of 10

1.86

1.26

0.0030

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