ALG08651.1 protein (Kibdelosporangium phytohabitans)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

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[Homology]

Score

ALG08651.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)

Predicted Functional Partners:

ALG11522.1

0.765

ALG09734.1

0.686

ALG12585.1

0.671

ALG11497.1

0.632

ALG14877.1

0.568

ALG08652.1

0.519

ALG08650.1

0.412

Your Current Organism:

Kibdelosporangium phytohabitans

NCBI taxonomy Id: 860235
Other names: CCTCC AA 2010001, K. phytohabitans, KCTC 19775, Kibdelosporangium phytohabitans Xing et al. 2012

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALG08650.1	ALG08651.1	AOZ06_18545	AOZ06_18550	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.412
ALG08651.1	ALG08650.1	AOZ06_18550	AOZ06_18545	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.412
ALG08651.1	ALG08652.1	AOZ06_18550	AOZ06_18560	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.519
ALG08651.1	ALG09734.1	AOZ06_18550	AOZ06_25055	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	5,10-methylene tetrahydromethanopterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.686
ALG08651.1	ALG11497.1	AOZ06_18550	AOZ06_35660	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	5,10-methylene tetrahydromethanopterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.632
ALG08651.1	ALG11522.1	AOZ06_18550	AOZ06_35810	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.765
ALG08651.1	ALG12585.1	AOZ06_18550	AOZ06_42125	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.671
ALG08651.1	ALG14877.1	AOZ06_18550	AOZ06_18555	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Thiamine biosynthesis protein ThiJ; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.568
ALG08652.1	ALG08651.1	AOZ06_18560	AOZ06_18550	Dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.519
ALG08652.1	ALG14877.1	AOZ06_18560	AOZ06_18555	Dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Thiamine biosynthesis protein ThiJ; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.490
ALG09734.1	ALG08651.1	AOZ06_25055	AOZ06_18550	5,10-methylene tetrahydromethanopterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.686
ALG11497.1	ALG08651.1	AOZ06_35660	AOZ06_18550	5,10-methylene tetrahydromethanopterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.632
ALG11522.1	ALG08651.1	AOZ06_35810	AOZ06_18550	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.765
ALG11522.1	ALG12585.1	AOZ06_35810	AOZ06_42125	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.504
ALG12585.1	ALG08651.1	AOZ06_42125	AOZ06_18550	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.671
ALG12585.1	ALG11522.1	AOZ06_42125	AOZ06_35810	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.504
ALG14877.1	ALG08651.1	AOZ06_18555	AOZ06_18550	Thiamine biosynthesis protein ThiJ; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.568
ALG14877.1	ALG08652.1	AOZ06_18555	AOZ06_18560	Thiamine biosynthesis protein ThiJ; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.490

Network Stats

number of nodes:

11

number of edges:

21

average node degree:

3.82

avg. local clustering coefficient:

0.874

expected number of edges:

14

PPI enrichment p-value:

0.0355

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006351

Transcription, DNA-templated

4 of 25

1.78

1.64

0.00033

GO:0016070

RNA metabolic process

6 of 116

1.29

1.26

0.00025

GO:0034654

Nucleobase-containing compound biosynthetic process

5 of 131

1.16

0.94

0.0019

GO:0010467

Gene expression

6 of 192

1.07

0.92

0.00088

GO:0009059

Macromolecule biosynthetic process

6 of 256

0.95

0.74

0.0025

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016779

Nucleotidyltransferase activity

6 of 41

1.74

2.6

3.89e-07

GO:0003899

DNA-directed 5-3 RNA polymerase activity

3 of 5

2.36

1.93

0.00023

GO:0140098

Catalytic activity, acting on RNA

5 of 73

1.41

1.39

0.00023

GO:0005488

Binding

11 of 1293

0.51

0.43

0.00023

GO:1901363

Heterocyclic compound binding

8 of 849

0.55

0.37

0.0185

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0061695

Transferase complex, transferring phosphorus-containing groups

4 of 13

2.07

2.51

7.01e-06

GO:0000428

DNA-directed RNA polymerase complex

3 of 6

2.28

2.26

4.35e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:325

RNA polymerase

3 of 5

2.36

1.68

0.00070

CL:1682

Mostly uncharacterized, incl. Cell morphogenesis, and GDP metabolic process

3 of 11

2.01

1.36

0.0023

CL:146

Ribosome, and Translation regulator activity

4 of 97

1.19

0.69

0.0215

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03020

RNA polymerase

3 of 4

2.45

2.26

5.73e-05

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-9635486

Infection with Mycobacterium tuberculosis

3 of 84

1.13

0.63

0.0279

MAP-5663205

Infectious disease

3 of 86

1.12

0.63

0.0279

MAP-1643685

Disease

3 of 92

1.09

0.61

0.0279

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0061695

Transferase complex, transferring phosphorus-containing groups

4 of 49

1.49

1.2

0.0017

GOCC:0000428

DNA-directed RNA polymerase complex

3 of 35

1.51

1.0

0.0064

GOCC:0005622

Intracellular

10 of 1115

0.53

0.42

0.0019

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0240

DNA-directed RNA polymerase

3 of 5

2.36

2.02

0.00015

KW-0548

Nucleotidyltransferase

4 of 33

1.66

1.67

0.00016

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