STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kynATryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (262 aa)    
Predicted Functional Partners:
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
 
 0.994
ALG11089.1
Kynureninase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.993
ALG14956.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.909
ALG08782.1
Tyrosine phenol-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.901
ALG07002.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
ALG09222.1
Amino acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
ALG11091.1
PaaX family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.839
trpA
Hypothetical protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.807
trpA-2
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.807
ALG12574.1
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.807
Your Current Organism:
Kibdelosporangium phytohabitans
NCBI taxonomy Id: 860235
Other names: CCTCC AA 2010001, K. phytohabitans, KCTC 19775, Kibdelosporangium phytohabitans Xing et al. 2012
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.