STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dot1Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (546 aa)    
Predicted Functional Partners:
HHT1
Histone H3; Belongs to the histone H3 family.
   
 0.986
SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
   
 0.953
SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
   
 0.928
UBI4
Polyubiquitin.
    
   0.923
CLCR_02433
GRF zinc finger domain-containing protein.
   
 0.916
CLCR_07668
Uncharacterized protein.
   
 0.916
CLCR_10124
Tat pathway signal sequence.
   
 0.916
hta1
Histone H2A; Belongs to the histone H2A family.
    
 
 0.915
CLCR_00756
Uncharacterized protein.
    
 0.900
CLCR_04030
Uncharacterized protein.
   
 0.894
Your Current Organism:
Cladophialophora carrionii
NCBI taxonomy Id: 86049
Other names: C. carrionii, CBS 160.54, Cladosporium carrionii
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.