node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APT1 | CLCR_03003 | A0A1C1CZT9 | A0A1C1D1Z5 | Adenine phosphoribosyltransferase. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.859 |
APT1 | CLCR_03916 | A0A1C1CZT9 | A0A1C1CI19 | Adenine phosphoribosyltransferase. | Putative pyrophosphatase/phosphodiesterase. | 0.790 |
APT1 | CLCR_04523 | A0A1C1CZT9 | A0A1C1CK81 | Adenine phosphoribosyltransferase. | Putative AMP deaminase. | 0.927 |
APT1 | CLCR_06864 | A0A1C1CZT9 | A0A1C1CM43 | Adenine phosphoribosyltransferase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.879 |
APT1 | GUA1 | A0A1C1CZT9 | A0A1C1C7J4 | Adenine phosphoribosyltransferase. | GMP synthase [glutamine-hydrolyzing]. | 0.969 |
APT1 | gda1 | A0A1C1CZT9 | A0A1C1CAD8 | Adenine phosphoribosyltransferase. | Putative guanosine-diphosphatase; Belongs to the GDA1/CD39 NTPase family. | 0.795 |
APT1 | ndk1 | A0A1C1CZT9 | A0A1C1CAZ7 | Adenine phosphoribosyltransferase. | Nucleoside diphosphate kinase. | 0.530 |
APT1 | ura7 | A0A1C1CZT9 | A0A1C1CIH7 | Adenine phosphoribosyltransferase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.690 |
CLCR_03003 | APT1 | A0A1C1D1Z5 | A0A1C1CZT9 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenine phosphoribosyltransferase. | 0.859 |
CLCR_03003 | CLCR_03916 | A0A1C1D1Z5 | A0A1C1CI19 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Putative pyrophosphatase/phosphodiesterase. | 0.803 |
CLCR_03003 | CLCR_04523 | A0A1C1D1Z5 | A0A1C1CK81 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Putative AMP deaminase. | 0.846 |
CLCR_03003 | CLCR_06864 | A0A1C1D1Z5 | A0A1C1CM43 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.921 |
CLCR_03003 | GUA1 | A0A1C1D1Z5 | A0A1C1C7J4 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase [glutamine-hydrolyzing]. | 0.914 |
CLCR_03003 | YND1 | A0A1C1D1Z5 | A0A1C1C7W1 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Golgi apyrase; Belongs to the GDA1/CD39 NTPase family. | 0.825 |
CLCR_03003 | gda1 | A0A1C1D1Z5 | A0A1C1CAD8 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Putative guanosine-diphosphatase; Belongs to the GDA1/CD39 NTPase family. | 0.810 |
CLCR_03003 | ndk1 | A0A1C1D1Z5 | A0A1C1CAZ7 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Nucleoside diphosphate kinase. | 0.916 |
CLCR_03003 | ura7 | A0A1C1D1Z5 | A0A1C1CIH7 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.900 |
CLCR_03916 | APT1 | A0A1C1CI19 | A0A1C1CZT9 | Putative pyrophosphatase/phosphodiesterase. | Adenine phosphoribosyltransferase. | 0.790 |
CLCR_03916 | CLCR_03003 | A0A1C1CI19 | A0A1C1D1Z5 | Putative pyrophosphatase/phosphodiesterase. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.803 |
CLCR_03916 | CLCR_04523 | A0A1C1CI19 | A0A1C1CK81 | Putative pyrophosphatase/phosphodiesterase. | Putative AMP deaminase. | 0.864 |