STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRS5Ribose-phosphate pyrophosphokinase 5. (452 aa)    
Predicted Functional Partners:
CLCR_01156
Ribose-phosphate pyrophosphokinase 1.
  
0.942
DIN4
2-oxoisovalerate dehydrogenase subunit beta 2, mitochondrial.
   
 0.909
PDB1
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.909
CLCR_05499
Putative transketolase.
   
 
 0.867
ADE4
Amidophosphoribosyltransferase.
  
 0.864
CLCR_02413
3-hydroxyisobutyrate dehydrogenase.
   
 
 0.863
RBK1
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
   
 0.863
CLCR_03066
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
   
 
 0.863
HIS1
ATP phosphoribosyltransferase.
  
 
 0.860
CLCR_09207
Putative ribose 5-phosphate isomerase.
    
 0.853
Your Current Organism:
Cladophialophora carrionii
NCBI taxonomy Id: 86049
Other names: C. carrionii, CBS 160.54, Cladosporium carrionii
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