STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
his3Histidinol-phosphate aminotransferase. (442 aa)    
Predicted Functional Partners:
CLCR_06629
Histidine biosynthesis trifunctional protein.
 
 0.999
HIS3
Imidazoleglycerol-phosphate dehydratase.
 
 0.999
hisHF
Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.
 
 
 0.994
tyr1
Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family.
  
 
 0.987
CLCR_09677
Tryptophan synthase.
  
  
 0.986
RAD16
DNA repair protein RAD16.
  
 
 0.983
pnk1
Bifunctional polynucleotide phosphatase/kinase.
  
 
 0.980
HIS1
ATP phosphoribosyltransferase.
 
  
 0.978
CLCR_11446
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Belongs to the HisA/HisF family.
  
  
 0.967
HOM3
Aspartokinase.
  
 
 0.966
Your Current Organism:
Cladophialophora carrionii
NCBI taxonomy Id: 86049
Other names: C. carrionii, CBS 160.54, Cladosporium carrionii
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.