UBC12 protein (Cladophialophora carrionii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

UBC12

NEDD8-conjugating enzyme UBC12; Belongs to the ubiquitin-conjugating enzyme family. (202 aa)

Predicted Functional Partners:

CLCR_05264

0.999

uba3

0.986

dcn1

0.985

Roc1a

0.985

nae1

0.983

CUL1

0.945

cul3b

0.944

UBA1

0.939

uba2

0.926

ATG7

0.905

Your Current Organism:

Cladophialophora carrionii

NCBI taxonomy Id: 86049
Other names: C. carrionii, CBS 160.54, Cladosporium carrionii

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG7	CLCR_05264	A0A1C1CCP8	A0A1C1CJC5	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	Ubiquitin-like domain-containing protein.	0.646
ATG7	CUL1	A0A1C1CCP8	A0A1C1CXY7	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	Cullin-1; Belongs to the cullin family.	0.785
ATG7	Roc1a	A0A1C1CCP8	A0A1C1CQ91	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	RING-box protein 1A.	0.666
ATG7	UBA1	A0A1C1CCP8	A0A1C1C889	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	Ubiquitin-activating enzyme E1 1; Belongs to the ubiquitin-activating E1 family.	0.836
ATG7	UBC12	A0A1C1CCP8	A0A1C1CH91	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	NEDD8-conjugating enzyme UBC12; Belongs to the ubiquitin-conjugating enzyme family.	0.905
ATG7	cul3b	A0A1C1CCP8	A0A1C1CD22	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	Cullin-3-B; Belongs to the cullin family.	0.785
ATG7	dcn1	A0A1C1CCP8	A0A1C1C9X1	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.	0.661
ATG7	uba3	A0A1C1CCP8	A0A1C1CLE0	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	NEDD8-activating enzyme E1 catalytic subunit.	0.807
CLCR_05264	ATG7	A0A1C1CJC5	A0A1C1CCP8	Ubiquitin-like domain-containing protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	0.646
CLCR_05264	CUL1	A0A1C1CJC5	A0A1C1CXY7	Ubiquitin-like domain-containing protein.	Cullin-1; Belongs to the cullin family.	0.975
CLCR_05264	Roc1a	A0A1C1CJC5	A0A1C1CQ91	Ubiquitin-like domain-containing protein.	RING-box protein 1A.	0.977
CLCR_05264	UBA1	A0A1C1CJC5	A0A1C1C889	Ubiquitin-like domain-containing protein.	Ubiquitin-activating enzyme E1 1; Belongs to the ubiquitin-activating E1 family.	0.883
CLCR_05264	UBC12	A0A1C1CJC5	A0A1C1CH91	Ubiquitin-like domain-containing protein.	NEDD8-conjugating enzyme UBC12; Belongs to the ubiquitin-conjugating enzyme family.	0.999
CLCR_05264	cul3b	A0A1C1CJC5	A0A1C1CD22	Ubiquitin-like domain-containing protein.	Cullin-3-B; Belongs to the cullin family.	0.975
CLCR_05264	dcn1	A0A1C1CJC5	A0A1C1C9X1	Ubiquitin-like domain-containing protein.	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.	0.928
CLCR_05264	nae1	A0A1C1CJC5	A0A1C1C966	Ubiquitin-like domain-containing protein.	NEDD8-activating enzyme E1 regulatory subunit.	0.986
CLCR_05264	uba2	A0A1C1CJC5	A0A1C1C8Q1	Ubiquitin-like domain-containing protein.	Ubiquitin-activating enzyme E1-like; Belongs to the ubiquitin-activating E1 family.	0.793
CLCR_05264	uba3	A0A1C1CJC5	A0A1C1CLE0	Ubiquitin-like domain-containing protein.	NEDD8-activating enzyme E1 catalytic subunit.	0.999
CUL1	ATG7	A0A1C1CXY7	A0A1C1CCP8	Cullin-1; Belongs to the cullin family.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	0.785
CUL1	CLCR_05264	A0A1C1CXY7	A0A1C1CJC5	Cullin-1; Belongs to the cullin family.	Ubiquitin-like domain-containing protein.	0.975