STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgp1tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. (452 aa)    
Predicted Functional Partners:
bud32
EKC/KEOPS complex subunit bud32.
  
 0.955
cgi121
EKC/KEOPS complex subunit cgi121; Belongs to the CGI121/TPRKB family.
    
 0.954
UTP18
U3 small nucleolar RNA-associated protein 18.
 
 
    0.900
CLCR_04036
Translation factor.
  
 
 0.877
stp1
Low molecular weight phosphotyrosine protein phosphatase.
    
  0.717
CAB5
Dephospho-CoA kinase CAB5.
    
 0.711
KAE1
tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...]
    
 
0.505
CLCR_00139
Peptidyl-tRNA hydrolase domain protein.
   
 
 0.503
CLCR_03819
Leucine--tRNA ligase, cytoplasmic.
   
 
 0.499
CLCR_09548
Leucine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
 0.499
Your Current Organism:
Cladophialophora carrionii
NCBI taxonomy Id: 86049
Other names: C. carrionii, CBS 160.54, Cladosporium carrionii
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