node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADK2 | APT1 | A0A1C1CS50 | A0A1C1CZT9 | GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | Adenine phosphoribosyltransferase. | 0.860 |
ADK2 | CLCR_03003 | A0A1C1CS50 | A0A1C1D1Z5 | GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.799 |
ADK2 | CLCR_07974 | A0A1C1CS50 | A0A1C1CU97 | GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.837 |
ADK2 | OLA1 | A0A1C1CS50 | A0A1C1CUT6 | GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | Obg-like ATPase 1. | 0.791 |
ADK2 | adk1 | A0A1C1CS50 | A0A1C1CAK1 | GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. | 0.815 |
ADK2 | gda1 | A0A1C1CS50 | A0A1C1CAD8 | GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | Putative guanosine-diphosphatase; Belongs to the GDA1/CD39 NTPase family. | 0.771 |
ADK2 | ndk1 | A0A1C1CS50 | A0A1C1CAZ7 | GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | Nucleoside diphosphate kinase. | 0.874 |
ADK2 | pkiA | A0A1C1CS50 | A0A1C1CDC8 | GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.838 |
ADK2 | ura7 | A0A1C1CS50 | A0A1C1CIH7 | GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.808 |
APT1 | ADK2 | A0A1C1CZT9 | A0A1C1CS50 | Adenine phosphoribosyltransferase. | GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | 0.860 |
APT1 | CLCR_03003 | A0A1C1CZT9 | A0A1C1D1Z5 | Adenine phosphoribosyltransferase. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.859 |
APT1 | OLA1 | A0A1C1CZT9 | A0A1C1CUT6 | Adenine phosphoribosyltransferase. | Obg-like ATPase 1. | 0.810 |
APT1 | adk1 | A0A1C1CZT9 | A0A1C1CAK1 | Adenine phosphoribosyltransferase. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. | 0.901 |
APT1 | gda1 | A0A1C1CZT9 | A0A1C1CAD8 | Adenine phosphoribosyltransferase. | Putative guanosine-diphosphatase; Belongs to the GDA1/CD39 NTPase family. | 0.795 |
APT1 | ndk1 | A0A1C1CZT9 | A0A1C1CAZ7 | Adenine phosphoribosyltransferase. | Nucleoside diphosphate kinase. | 0.530 |
APT1 | ura7 | A0A1C1CZT9 | A0A1C1CIH7 | Adenine phosphoribosyltransferase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.690 |
CLCR_03003 | ADK2 | A0A1C1D1Z5 | A0A1C1CS50 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | 0.799 |
CLCR_03003 | APT1 | A0A1C1D1Z5 | A0A1C1CZT9 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenine phosphoribosyltransferase. | 0.859 |
CLCR_03003 | CLCR_07974 | A0A1C1D1Z5 | A0A1C1CU97 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.818 |
CLCR_03003 | OLA1 | A0A1C1D1Z5 | A0A1C1CUT6 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Obg-like ATPase 1. | 0.800 |