STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ubc8Ubiquitin-conjugating enzyme E2 8; Belongs to the ubiquitin-conjugating enzyme family. (186 aa)    
Predicted Functional Partners:
UBA1
Ubiquitin-activating enzyme E1 1; Belongs to the ubiquitin-activating E1 family.
    
 0.921
uba3
NEDD8-activating enzyme E1 catalytic subunit.
    
 0.868
CLCR_08938
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.849
CLCR_05992
Putative ubiquitin-conjugating enzyme.
   
 0.832
UBC6
Ubiquitin-conjugating enzyme E2 6.
     
 0.826
spm2
Ubiquitin-conjugating enzyme spm2.
     
 0.808
ATG7
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
    
 0.802
nae1
NEDD8-activating enzyme E1 regulatory subunit.
    
 0.801
ubc1
Ubiquitin-conjugating enzyme E2 1; Belongs to the ubiquitin-conjugating enzyme family.
   
0.787
CLCR_02241
Ubiquitin conjugating enzyme.
   
 0.776
Your Current Organism:
Cladophialophora carrionii
NCBI taxonomy Id: 86049
Other names: C. carrionii, CBS 160.54, Cladosporium carrionii
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