node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFT38271.1 | SFT43774.1 | SAMN04515657_0213 | SAMN04515657_0525 | DNA polymerase III, delta subunit. | DNA polymerase III, delta prime subunit. | 0.994 |
SFT38271.1 | SFT50319.1 | SAMN04515657_0213 | SAMN04515657_0894 | DNA polymerase III, delta subunit. | DNA polymerase III, alpha subunit. | 0.979 |
SFT38271.1 | SFT64975.1 | SAMN04515657_0213 | SAMN04515657_1497 | DNA polymerase III, delta subunit. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.997 |
SFT38271.1 | SFT79620.1 | SAMN04515657_0213 | SAMN04515657_2223 | DNA polymerase III, delta subunit. | DNA polymerase III, chi subunit. | 0.986 |
SFT38271.1 | SFT84570.1 | SAMN04515657_0213 | SAMN04515657_2396 | DNA polymerase III, delta subunit. | ATP-dependent DNA helicase RecQ. | 0.718 |
SFT38271.1 | dnaE2 | SAMN04515657_0213 | SAMN04515657_1439 | DNA polymerase III, delta subunit. | Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.976 |
SFT38271.1 | dnaX | SAMN04515657_0213 | SAMN04515657_1062 | DNA polymerase III, delta subunit. | DNA polymerase III, gamma subunit /DNA polymerase III, tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.997 |
SFT38271.1 | lexA | SAMN04515657_0213 | SAMN04515657_1177 | DNA polymerase III, delta subunit. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.806 |
SFT38271.1 | rnt | SAMN04515657_0213 | SAMN04515657_1024 | DNA polymerase III, delta subunit. | RNAse T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | 0.833 |
SFT43774.1 | SFT38271.1 | SAMN04515657_0525 | SAMN04515657_0213 | DNA polymerase III, delta prime subunit. | DNA polymerase III, delta subunit. | 0.994 |
SFT43774.1 | SFT50319.1 | SAMN04515657_0525 | SAMN04515657_0894 | DNA polymerase III, delta prime subunit. | DNA polymerase III, alpha subunit. | 0.980 |
SFT43774.1 | SFT64975.1 | SAMN04515657_0525 | SAMN04515657_1497 | DNA polymerase III, delta prime subunit. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.995 |
SFT43774.1 | SFT79620.1 | SAMN04515657_0525 | SAMN04515657_2223 | DNA polymerase III, delta prime subunit. | DNA polymerase III, chi subunit. | 0.993 |
SFT43774.1 | SFT84570.1 | SAMN04515657_0525 | SAMN04515657_2396 | DNA polymerase III, delta prime subunit. | ATP-dependent DNA helicase RecQ. | 0.840 |
SFT43774.1 | dnaE2 | SAMN04515657_0525 | SAMN04515657_1439 | DNA polymerase III, delta prime subunit. | Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.972 |
SFT43774.1 | dnaX | SAMN04515657_0525 | SAMN04515657_1062 | DNA polymerase III, delta prime subunit. | DNA polymerase III, gamma subunit /DNA polymerase III, tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.996 |
SFT43774.1 | lexA | SAMN04515657_0525 | SAMN04515657_1177 | DNA polymerase III, delta prime subunit. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.739 |
SFT43774.1 | parE | SAMN04515657_0525 | SAMN04515657_2217 | DNA polymerase III, delta prime subunit. | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.485 |
SFT43774.1 | rnt | SAMN04515657_0525 | SAMN04515657_1024 | DNA polymerase III, delta prime subunit. | RNAse T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | 0.788 |
SFT50319.1 | SFT38271.1 | SAMN04515657_0894 | SAMN04515657_0213 | DNA polymerase III, alpha subunit. | DNA polymerase III, delta subunit. | 0.979 |