Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KPD23210.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.961
KPD23211.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.664
KPD23922.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.502
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.495
KPD23073.1
Deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.488
KPD23487.1
Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.470
KPD23068.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.464
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
    
  0.450
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.444
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
 0.441
Your Current Organism:
Idiomarina zobellii
NCBI taxonomy Id: 86103
Other names: ATCC BAA-313, I. zobellii, Idiomarina zobellii Ivanova et al. 2000, KMM 231, marine bacterium KM231
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