STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dapB_24-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (270 aa)    
Predicted Functional Partners:
dapA_2
4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
 
 0.984
dapD_2
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Product derived from UniProtKB/Swiss-Prot:Q4FTR7;Gene name derived from UniProtKB/Swiss-Prot:Q4FTR7;EC number derived from UniProtKB/Swiss-Prot:Q4FTR7; Belongs to the transferase hexapeptide repeat family.
 
 
 0.912
pcnB_2
PolyApolymerase family protein; Product derived from UniProtKB/Trembl:F7XWY6;Gene name derived from UniProtKB/Trembl:F7XWY6;EC number derived from UniProtKB/Trembl:F7XWY6; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
    0.885
aatA_2
Aspartate aminotransferase; Product derived from UniProtKB/Swiss-Prot:Q4UND3;Gene name derived from UniProtKB/Swiss-Prot:Q4UND3;EC number derived from UniProtKB/Swiss-Prot:Q4UND3.
    
 0.871
lysC_2
Aspartokinase; Product derived from UniProtKB/Swiss-Prot:O69077;Gene name derived from UniProtKB/Swiss-Prot:O69077;EC number derived from UniProtKB/Swiss-Prot:O69077; Belongs to the aspartokinase family.
 
 
 0.855
asd_2
Aspartate-semialdehyde dehydrogenase; Product derived from UniProtKB/Swiss-Prot:Q1RIB3;Gene name derived from UniProtKB/Swiss-Prot:Q1RIB3;EC number derived from UniProtKB/Swiss-Prot:Q1RIB3; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
 
 0.809
dapE_2
Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
   
 0.779
KIE05391.1
Uncharacterized protein; Product derived from UniProtKB/Trembl:K2LEF4; Belongs to the LOG family.
       0.773
dnaJ_2
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
 
  
 0.769
KIE05095.1
NADH-ubiquinone oxidoreductase family protein; Product derived from UniProtKB/Trembl:F0IXB2.
  
 
  0.767
Your Current Organism:
Jidaibacter acanthamoeba
NCBI taxonomy Id: 86105
Other names: C. Jidaibacter acanthamoeba, Candidatus Jidaibacter acanthamoeba, endosymbiont of Acanthamoeba sp. UWC36
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.