STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppnK_2Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (264 aa)    
Predicted Functional Partners:
nadE_2
Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
  
 0.916
KIE06200.1
Hypothetical protein.
    
  0.839
KIE05177.1
Hypothetical protein.
    
  0.839
nadD_2
Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.825
KIE04991.1
Putative protease IV; Product derived from UniProtKB/Trembl:Q68WL1;EC number derived from UniProtKB/Trembl:Q68WL1.
    
  0.822
KIE04319.1
Hypothetical protein; Product derived from UniProtKB/Trembl:F7XV75.
    
  0.822
gabD_2
Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; Product derived from UniProtKB/Swiss-Prot:P25526;Gene name derived from UniProtKB/Swiss-Prot:P25526;EC number derived from UniProtKB/Swiss-Prot:P25526; Belongs to the aldehyde dehydrogenase family.
   
 0.815
KIE05989.1
Hypothetical protein.
     
 0.813
tme_2
NADP-dependent malic enzyme; Product derived from UniProtKB/Swiss-Prot:O30808;Gene name derived from UniProtKB/Swiss-Prot:O30808;EC number derived from UniProtKB/Swiss-Prot:O30808.
   
 0.806
rnhA_2
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
    
  0.793
Your Current Organism:
Jidaibacter acanthamoeba
NCBI taxonomy Id: 86105
Other names: C. Jidaibacter acanthamoeba, Candidatus Jidaibacter acanthamoeba, endosymbiont of Acanthamoeba sp. UWC36
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