STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iscS_2Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (406 aa)    
Predicted Functional Partners:
nifU_2
NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
 
 0.999
KIE04830.1
Product derived from UniProtKB/Swiss-Prot:P44675; putative HTH-type transcriptional regulator HI_0379.
 
 
 0.998
fdxB_2
2Fe-2S ferredoxin; Product derived from UniProtKB/Swiss-Prot:Q9AKM6;Gene name derived from UniProtKB/Swiss-Prot:Q9AKM6.
 0.985
nifS_2
Cysteine desulfurase 2; Product derived from UniProtKB/Trembl:F7XV99;Gene name derived from UniProtKB/Trembl:F7XV99;EC number derived from UniProtKB/Trembl:F7XV99.
 
  
 
0.959
KIE04826.1
Uncharacterized protein; Product derived from UniProtKB/Swiss-Prot:Q9ZD62; Uncharacterized protein RP484; Belongs to the HesB/IscA family.
  
 
 0.947
acpP_2
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 
 0.895
nfu1_2
NFU1 iron-sulfur cluster scaffold-like protein; Product derived from UniProtKB/Swiss-Prot:Q9UMS0;Gene name derived from UniProtKB/Swiss-Prot:Q9UMS0.
 
 0.872
hscB
Hypothetical protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
  
 
 0.853
nsrR_2
HTH-type transcriptional regulator NsrR; Product derived from UniProtKB/Swiss-Prot:Q65M01;Gene name derived from UniProtKB/Swiss-Prot:Q65M01.
  
 
 0.838
KIE04952.1
Hypothetical protein.
    
 0.770
Your Current Organism:
Jidaibacter acanthamoeba
NCBI taxonomy Id: 86105
Other names: C. Jidaibacter acanthamoeba, Candidatus Jidaibacter acanthamoeba, endosymbiont of Acanthamoeba sp. UWC36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.