STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIF81536.1COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32). (328 aa)    
Predicted Functional Partners:
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
     0.992
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.904
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
 
 0.897
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.891
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.876
nusA
Transcription elongation factor NusA; Participates in both transcription termination and antitermination.
  
 
 0.829
AIF80991.1
COG1329 Transcriptional regulators, similar to M. xanthus CarD.
   
 
 0.772
AIF81535.1
Hypothetical protein.
       0.757
AIF80673.1
COG0625 Glutathione S-transferase; Belongs to the GST superfamily.
    
   0.690
AIF81818.1
COG0625 Glutathione S-transferase.
    
   0.690
Your Current Organism:
endosymbiont of Acanthamoeba
NCBI taxonomy Id: 86106
Other names: e. of Acanthamoeba sp. UWC8, endosymbiont of Acanthamoeba sp. UWC8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.