STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDH00833.1DnaJ domain-containing protein. (209 aa)    
Predicted Functional Partners:
SDI08795.1
HxxPF-repeated domain-containing protein.
  
 
 0.999
htpG
Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity.
  
 0.995
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
 
 
 0.980
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.958
SDG75730.1
Hypothetical chaperone protein.
  
 0.953
SDH11276.1
Molecular chaperone DnaK (HSP70).
  
 0.953
SDH11297.1
Molecular chaperone DnaK (HSP70); Belongs to the heat shock protein 70 family.
  
 0.953
SDH13987.1
Plasmid segregation actin-type ATPase ParM.
  
 0.953
hscA
Molecular chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
  
 0.953
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.917
Your Current Organism:
Vibrio xiamenensis
NCBI taxonomy Id: 861298
Other names: CGMCC 1.10228, DSM 22851, V. xiamenensis, Vibrio sp. G21, Vibrio xiamenensis Gao et al. 2012, strain G21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.