STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
J421_4543acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (435 aa)    
Predicted Functional Partners:
J421_4417
3-hydroxyacyl-CoA dehydrogenase NAD-binding protein.
 
 0.999
J421_4542
Enoyl-CoA hydratase/isomerase.
 0.999
J421_3934
acyl-CoA dehydrogenase domain-containing protein.
  
 0.943
J421_3418
Carboxyl transferase.
  
 0.931
J421_3000
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 
0.921
J421_4418
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 
0.917
J421_3037
Methylmalonate-semialdehyde dehydrogenase.
   
 0.907
J421_3036
Malate synthase A; Belongs to the malate synthase family.
   
 
 0.893
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.878
J421_1490
2-oxoacid:acceptor oxidoreductase, alpha subunit.
  
 
 0.869
Your Current Organism:
Gemmatirosa kalamazoonesis
NCBI taxonomy Id: 861299
Other names: ATCC BAA-2150, G. kalamazoonesis, Gemmatimonadetes bacterium KBS708, NCCB 100411, strain KBS708
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.