STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
umuDPutative DNA polymerase subunit UmuD; In Escherichia coli umuD and umuC genes have been shown to encode E. coli s fifth DNA polymerase, pol V (consisting of a heterotrimer of UmuD (2)C). The main function of pol V appears to be the bypass of DNA lesions that would otherwise block replication by pols I-IV; Belongs to the peptidase S24 family. (138 aa)    
Predicted Functional Partners:
umuC
Putative DNA polymerase subunit UmuC; In Escherichia coli umuD and umuC genes have been shown to encode E. coli s fifth DNA polymerase, pol V (consisting of a heterotrimer of UmuD (2)C). The main function of pol V appears to be the bypass of DNA lesions that would otherwise block replication by pols I-IV.
 
 
 0.984
recA
RecA bacterial DNA recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.931
dinB
Putative DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
 
 0.828
tctB
Putative citrate transport protein TctB; Possible TctB component of the TctCBA citrate uptake system (TC 2.A.1.1).
      
 0.769
ftsX
Cell division membrane protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
      
 0.769
recN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
   
  
 0.624
AARI_03520
Glycosyl hydrolase, family 3; Identified by match to PF00933. Glycoside hydrolase family 3 comprises enzymes with a number of known activities; beta-glucosidase (EC:3.2.1.21); beta-xylosidase (EC:3.2.1.37); N-acetyl beta-glucosaminidase (EC:3.2.1.52); glucan beta-1,3-glucosidase (EC:3.2.1.58); cellodextrinase (EC:3.2.1.74); exo-1,3-1,4-glucanase (EC:3. 2.1).
       0.580
AARI_02880
AraC-family transcriptional regulator; Identified by match to protein domain PF00165: bacterial regulatory helix-turn-helix proteins, AraC family.
   
 
 0.446
ruvA
Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
  
  
 0.437
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
  
  
 0.423
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
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