STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AARI_04010AraC-family transcriptional regulator; Identified by match to protein domain PF00165: bacterial regulatory helix-turn-helix proteins, AraC family. (529 aa)    
Predicted Functional Partners:
AARI_04000
Putative siderophore-interacting protein; Identified by match to protein family PF04954. Match to protein domain PF08021. Possibly involved in removal of iron from iron-siderophore complexes.
 
    0.671
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.599
lysG
Lysine export transcriptional regulatory protein LysG; Probable transcriptional regulator of lysE. Identified by similarity to protein SP: P94632 (Corynebacterium glutamicum); Belongs to the LysR transcriptional regulatory family.
  
  
 0.543
AARI_16680
GntR-family transcriptional regulator; Identified by match to protein family PF00392. This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerisation domain. The GntR-like proteins can be divided into six sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships.
   
  
 0.519
npdA
Putative NAD-dependent deacetylase; Identified by match to PF02146: Sir2 family. Sir2 proteins, also known as sirtuins, are found in all eukaryotes and many archaea and prokaryotes and have been shown to regulate gene silencing, DNA repair, metabolic enzymes, and life span. Function: modulate the activities of several enzymes which are inactive in their acetylated form. Catalytic activity: NAD+ + an acetylprotein = nicotinamide + O-acetyl-ADP-ribose + a protein.
  
  
 0.476
AARI_02880
AraC-family transcriptional regulator; Identified by match to protein domain PF00165: bacterial regulatory helix-turn-helix proteins, AraC family.
 
 
0.452
AARI_03980
Iron-siderophore ABC transporter, substrate-binding protein; TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, binding protein (BP), ISVH-family (iron siderophores, vitamin B12 and hemin).
  
  
 0.402
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
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