STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pobACatalyses the following reaction: 4-hydroxybenzoate + NADPH + O(2) <=> protocatechuate + NADP(+) + H(2)O. (398 aa)    
Predicted Functional Partners:
pcaG
Protocatechuate 3,4-dioxygenase subunit alpha; Catalyses the following reaction: 3,4-dihydroxybenzoate + O(2) <=> 3-carboxy-cis,cis-muconate.
 
 
 0.993
pcaH
Protocatechuate 3,4-dioxygenase subunit beta; Catalyses the following reaction: 3,4-dihydroxybenzoate + O(2) <=> 3-carboxy-cis,cis-muconate.
 
 0.993
pcaB
Catalyses the cyclization of 3-carboxy-cis,cis-muconate to 4-carboxy-muconolactone. Involved in aromatic acids catabolism.
 
  
 0.882
pcaC
4-carboxymuconolactone decarboxylase; Involved in protocatechuate catabolism.
 
  
 0.862
pcaD
3-oxoadipate enol-lactonase catalyses the formation of 3-oxoadipate from 3-oxoadipate enol-lactone. It is involved in aromatic acids catabolism.
 
  
 0.819
paaF
phenylacetate--CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
      
 0.789
catA
Catechol 1,2-dioxygenase; Catalyses the third step in the catabolism of catechol to succinyl-CoA and acetyl-CoA in the beta-ketoadipate pathway: the intradiol cleavage reaction of catechol to form cis,cis-muconate.
 
  
 0.703
AARI_04430
IclR-family transcriptional regulator; Identified by match to PF09339: IclR helix-turn-helix domain. This family of bacterial transcriptional regulators groups several proteins, including gylR, a possible activator protein for the gylABX glycerol operon in Streptomyces, and iclR, the repressor of the acetate operon (also known as glyoxylate bypass operon) in Escherichia coli and Salmonella typhimurium.
 
   
 0.568
AARI_09490
Putative cytochrome P450.
 
 
 0.543
AARI_04480
IclR-family transcriptional regulator; Identified by match to PF09339: IclR helix-turn-helix domain. This family of bacterial transcriptional regulators groups several proteins, including gylR, a possible activator protein for the gylABX glycerol operon in Streptomyces, and iclR, the repressor of the acetate operon (also known as glyoxylate bypass operon) in Escherichia coli and Salmonella typhimurium.
 
   
 0.512
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
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