STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metBCystathionine gamma-synthase; Catalyzes the conversion of cysteine and succinyl-homoserine into cystathionine and succinate. Several other reactions may also be catalysed in some organisms. (385 aa)    
Predicted Functional Partners:
cysK
Cysteine synthase; Responsible for the formation of cysteine from O-acetyl-serine and hydrogen sulfide with the concomitant release of acetic acid; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.988
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Final step in methionine synthesis.
  
 
 0.985
metX
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
   
 0.976
AARI_24020
Catalyses the synthesis of L-cystathionine from L-serine and L-homocysteine.
 0.972
AARI_17900
Identified by match to PF00291: pyridoxal-phosphate dependent enzyme.
 
 0.958
sir
Sulfite reductase (ferredoxin); Catalyzes the reduction of sulfite to sulphide. Involved in the sulfate assimilation pathway; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 0.940
AARI_02460
O-acetylhomoserine aminocarboxypropyltransferase; Catalyses several reactions, including the formation of L-homocysteine from O-acetyl-L-homoserine and H2S, and the formation of L-methionine from O-acetyl-L- homoserine and methanethiol.
 
 
0.937
AARI_07000
O-acetylhomoserine aminocarboxypropyltransferase; Catalyses several reactions, including the formation of L-homocysteine from O-acetyl-L-homoserine and H2S, and the formation of L-methionine from O-acetyl-L- homoserine and methanethiol.
 
 
0.937
AARI_09180
O-acetylhomoserine aminocarboxypropyltransferase; Catalyses several reactions, including the formation of L-homocysteine from O-acetyl-L-homoserine and H2S, and the formation of L-methionine from O-acetyl-L- homoserine and methanethiol.
 
 
0.936
luxS
S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
 
 
 0.936
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.