STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
deoAThymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate. This enzyme regulates the availability of thymidine and is therefore essential to nucleic acid metabolism. (437 aa)    
Predicted Functional Partners:
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
 0.999
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
 
 0.963
deoD
Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
 
  
 0.961
tdk
Thymidine kinase; Catalyzes the formation of thymidine 5-phosphate from thymidine.
    
 0.927
AARI_02770
Putative 5'-nucleotidase family protein; 5 -nucleotidases are enzymes that catalyze the hydrolysis of phosphate esterified at carbon 5 of the ribose and deoxyribose portions of nucleotide molecules; Belongs to the 5'-nucleotidase family.
 
  
 0.924
pyrR
Bifunctional protein pyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.911
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
 
 
 0.890
AARI_07320
Putative sugar ABC transporter, inner membrane subunit; TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-2 (CUT2) family (TC 3.A.1. 2.z). ABCISSE: ABCISSE: ABC transporter, permease (IM), MOS-family (monosaccharides: pentoses and hexoses); Belongs to the binding-protein-dependent transport system permease family.
 
   
 0.762
AARI_07300
Putative sugar ABC transporter, ATP-binding subunit; TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-2 (CUT2) family (TC 3.A.1. 2.z). ABCISSE: ABCISSE: ABC transporter, fused ATP- binding protein (ABC2), MOS-family (monosaccharides: pentoses and hexoses).
     
 0.732
AARI_07310
Putative sugar ABC transporter, inner membrane subunit; TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-2 (CUT2) family (TC 3.A.1. 2.z). ABCISSE: ABCISSE: ABC transporter, permease (IM), MOS-family (monosaccharides: pentoses and hexoses); Belongs to the binding-protein-dependent transport system permease family.
     
 0.732
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
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