node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AARI_02770 | AARI_17760 | AARI_02770 | AARI_17760 | Putative 5'-nucleotidase family protein; 5 -nucleotidases are enzymes that catalyze the hydrolysis of phosphate esterified at carbon 5 of the ribose and deoxyribose portions of nucleotide molecules; Belongs to the 5'-nucleotidase family. | Uridine kinase-like protein; Uridine kinase catalyzes the phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, this enzyme combined with nucleoside diphosphate kinases further phosphorylates UMP and CMP to form UTP and CTP. | 0.918 |
AARI_02770 | pyrF | AARI_02770 | AARI_17120 | Putative 5'-nucleotidase family protein; 5 -nucleotidases are enzymes that catalyze the hydrolysis of phosphate esterified at carbon 5 of the ribose and deoxyribose portions of nucleotide molecules; Belongs to the 5'-nucleotidase family. | Orotidine-5'-phosphate decarboxylase; Decarboxylates orotidine-5-phosphate to form uridine 5-phosphate (UMP). Involved in pyrimidine biosynthesis; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.902 |
AARI_02770 | pyrH | AARI_02770 | AARI_09660 | Putative 5'-nucleotidase family protein; 5 -nucleotidases are enzymes that catalyze the hydrolysis of phosphate esterified at carbon 5 of the ribose and deoxyribose portions of nucleotide molecules; Belongs to the 5'-nucleotidase family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.901 |
AARI_02770 | pyrR | AARI_02770 | AARI_17180 | Putative 5'-nucleotidase family protein; 5 -nucleotidases are enzymes that catalyze the hydrolysis of phosphate esterified at carbon 5 of the ribose and deoxyribose portions of nucleotide molecules; Belongs to the 5'-nucleotidase family. | Bifunctional protein pyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.900 |
AARI_02770 | upp | AARI_02770 | AARI_04840 | Putative 5'-nucleotidase family protein; 5 -nucleotidases are enzymes that catalyze the hydrolysis of phosphate esterified at carbon 5 of the ribose and deoxyribose portions of nucleotide molecules; Belongs to the 5'-nucleotidase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.902 |
AARI_17760 | AARI_02770 | AARI_17760 | AARI_02770 | Uridine kinase-like protein; Uridine kinase catalyzes the phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, this enzyme combined with nucleoside diphosphate kinases further phosphorylates UMP and CMP to form UTP and CTP. | Putative 5'-nucleotidase family protein; 5 -nucleotidases are enzymes that catalyze the hydrolysis of phosphate esterified at carbon 5 of the ribose and deoxyribose portions of nucleotide molecules; Belongs to the 5'-nucleotidase family. | 0.918 |
AARI_17760 | pyrF | AARI_17760 | AARI_17120 | Uridine kinase-like protein; Uridine kinase catalyzes the phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, this enzyme combined with nucleoside diphosphate kinases further phosphorylates UMP and CMP to form UTP and CTP. | Orotidine-5'-phosphate decarboxylase; Decarboxylates orotidine-5-phosphate to form uridine 5-phosphate (UMP). Involved in pyrimidine biosynthesis; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.920 |
AARI_17760 | pyrH | AARI_17760 | AARI_09660 | Uridine kinase-like protein; Uridine kinase catalyzes the phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, this enzyme combined with nucleoside diphosphate kinases further phosphorylates UMP and CMP to form UTP and CTP. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.920 |
AARI_17760 | pyrR | AARI_17760 | AARI_17180 | Uridine kinase-like protein; Uridine kinase catalyzes the phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, this enzyme combined with nucleoside diphosphate kinases further phosphorylates UMP and CMP to form UTP and CTP. | Bifunctional protein pyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.909 |
AARI_17760 | upp | AARI_17760 | AARI_04840 | Uridine kinase-like protein; Uridine kinase catalyzes the phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, this enzyme combined with nucleoside diphosphate kinases further phosphorylates UMP and CMP to form UTP and CTP. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.979 |
cdsA | frr | AARI_09680 | AARI_09670 | Phosphatidate cytidylyltransferase catalyzes the synthesis of CDP-diacylglycerol from CTP and phosphatidate. It produces key intermediates in phospholipid biosynthesis; Belongs to the CDS family. | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.856 |
cdsA | pyrH | AARI_09680 | AARI_09660 | Phosphatidate cytidylyltransferase catalyzes the synthesis of CDP-diacylglycerol from CTP and phosphatidate. It produces key intermediates in phospholipid biosynthesis; Belongs to the CDS family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.862 |
cdsA | rpsB | AARI_09680 | AARI_09640 | Phosphatidate cytidylyltransferase catalyzes the synthesis of CDP-diacylglycerol from CTP and phosphatidate. It produces key intermediates in phospholipid biosynthesis; Belongs to the CDS family. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.471 |
cdsA | tsf | AARI_09680 | AARI_09650 | Phosphatidate cytidylyltransferase catalyzes the synthesis of CDP-diacylglycerol from CTP and phosphatidate. It produces key intermediates in phospholipid biosynthesis; Belongs to the CDS family. | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.629 |
frr | cdsA | AARI_09670 | AARI_09680 | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Phosphatidate cytidylyltransferase catalyzes the synthesis of CDP-diacylglycerol from CTP and phosphatidate. It produces key intermediates in phospholipid biosynthesis; Belongs to the CDS family. | 0.856 |
frr | ndk | AARI_09670 | AARI_18250 | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.741 |
frr | pyrH | AARI_09670 | AARI_09660 | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.995 |
frr | rpsB | AARI_09670 | AARI_09640 | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.996 |
frr | tsf | AARI_09670 | AARI_09650 | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.995 |
ndk | frr | AARI_18250 | AARI_09670 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.741 |