STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AARI_11090Putative methyltransferase; Match to protein domain PF05175. This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases. (201 aa)    
Predicted Functional Partners:
AARI_11110
Putative ATP-dependent helicase; Possible DNA or RNA helicase.
 
    0.614
AARI_19290
Putative methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
  
     0.587
hflX
Putative GTPase; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
       0.536
obg
Obg-family GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
   
  
 0.503
valS
valine-tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner.
  
     0.495
AARI_12870
Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.
  
     0.462
AARI_25460
ABC transporter, inner membrane and ATP-binding subunits; TC 3.A.1.y.z. ABCISSE for N-terminal section of the protein: ABC transporter, fused ATP-binding protein (ABC2), CBY-family (Cobalt uptake, unknown), Y179- subfamily (CBU-like systems); C-terminal section of the protein: permease (IM), CBY-family, Y179-subfamily. The function of CBU-like systems is unknown.
  
    0.433
rplA
50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
  
    0.424
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
    0.418
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.