STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AARI_11980Identified by match to protein family PF01656. Putative chromosome partitioning protein. (275 aa)    
Predicted Functional Partners:
parB
Putative chromosome-partitioning protein ParB; Identified by match to TIGR00180. This HMM represents the most well-conserved core of a set of chromosomal and plasmid partition proteins related to ParB, including Spo0J, RepB, and SopB. Spo0J has been shown to bind a specific DNA sequence that, when introduced into a plasmid, can serve as partition site. Study of RepB, which has nicking-closing activity, suggests that it forms a transient protein-DNA covalent intermediate during the strand transfer reaction.
 
 
 0.921
AARI_03840
Match to protein family PF02195. Proteins containing this domain, appear to be related to the Escherichia coli plasmid protein ParB, which preferentially cleaves single-stranded DNA.
  
 
 0.640
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 0.602
AARI_25670
Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.
 
     0.520
AARI_12830
Hypothetical membrane protein; 2 transmembrane helices predicted by TMHMM2.0.
  
     0.505
AARI_12090
FtsK/SpoIIIE domain-containing protein; Match to PF01580. This domain is found extensively in a wide variety of proteins from prokaryotes and plasmids.
  
  
 0.502
AARI_09610
Conserved hypothetical membrane protein; Signal peptide predicted by SignalP 3.0 HMM (probability: 0.990) with cleavage site probability 0.909 between position 29 and 30. 7 transmembrane helices predicted by TMHMM2.0 after the signal peptide.
  
    0.488
AARI_15940
Identified by match to PF00106. The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases. Possibly involved in the metabolism of lipid.
  
     0.485
ftsK
DNA translocase FtsK; DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind it.
  
  
 0.472
AARI_19480
Hypothetical membrane protein; 2 transmembranes helices predicted by TMHMM2.0.
  
     0.461
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
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