STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AARI_12010Putative fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A. Possibly involved in the degradation of lipids via beta-oxidation. (603 aa)    
Predicted Functional Partners:
AARI_04500
Triacylglycerol lipase hydrolyzes ester bonds in triacylglycerol giving diacylglycerol, monoacylglycerol, glycerol and free fatty acids. Signal peptide predicted by SignalP 3.0 HMM (probability: 1) with cleavage site probability 0.991 between position 34 and 35.
   
 
 0.819
AARI_14830
5.2 Protein of unknown function similar to proteins from other organisms.
   
 
 0.819
AARI_18740
Putative fatty-acid--Co-A ligase; Match to protein family PF00501. This family of enzymes includes luciferase, long chain fatty acid Co-A ligase, acetyl-CoA synthetase and various other closely-related synthetases.
 
 
 0.753
AARI_29000
Putative fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A. Possibly involved in the synthesis of cellular lipids or their degradation via beta-oxidation.
 
 
0.710
AARI_28430
Putative fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A. Possibly involved in the synthesis of cellular lipids or their degradation via beta-oxidation.
 
 
0.677
aco
acyl-CoA oxidase; Identified by similarity to potein SP:Q33DR0 (Arthrobacter ureafaciens). Catalyzes the oxidation of acyl-coenzyme A (acyl-CoA) thioester to the corresponding trans-2-enoyl-CoA thioester: acyl-CoA + O2 --> trans-2-enoyl-CoA + H2O2. Probably involved in beta-oxidation of fatty acids.
 
 0.667
rplE
50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
    
 
 0.626
AARI_07800
Putative fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A. Possibly involved in the synthesis of cellular lipids or their degradation via beta-oxidation.
  
  
 
0.624
AARI_02570
Putative acyl-CoA dehydrogenase; Possibly involved in the metabolism of lipids. Match to PF08028. Acyl-CoA dehydrogenases catalyze the alpha,beta-dehydrogenation of acyl-CoA thioesters to the corresponding trans 2,3-enoyl CoA-products with concommitant reduction of enzyme-bound FAD.
  
 0.612
AARI_02680
Putative acyl-CoA dehydrogenase; Possibly involved in the metabolism of lipids. Match to PF08028. Acyl-CoA dehydrogenases catalyze the alpha,beta-dehydrogenation of acyl-CoA thioesters to the corresponding trans 2,3-enoyl CoA-products with concommitant reduction of enzyme-bound FAD.
  
 0.612
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
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