node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AARI_00040 | AARI_07810 | AARI_00040 | AARI_07810 | Conserved hypothetical protein; Match to protein family PF05258. This family contains several actinomycete proteins of unknown function. | Putative dolichyl-phosphate-mannose-protein mannosyltransferase; Identified by match to protein family PF02366. Transfers mannosyl residues to the hydroxy of serine or threonine residues, producing cell-wall mannoproteins. | 0.767 |
AARI_00040 | AARI_12650 | AARI_00040 | AARI_12650 | Conserved hypothetical protein; Match to protein family PF05258. This family contains several actinomycete proteins of unknown function. | Putative Sua5 family translation factor; Belongs to the SUA5 family. | 0.503 |
AARI_07810 | AARI_00040 | AARI_07810 | AARI_00040 | Putative dolichyl-phosphate-mannose-protein mannosyltransferase; Identified by match to protein family PF02366. Transfers mannosyl residues to the hydroxy of serine or threonine residues, producing cell-wall mannoproteins. | Conserved hypothetical protein; Match to protein family PF05258. This family contains several actinomycete proteins of unknown function. | 0.767 |
AARI_07810 | AARI_12650 | AARI_07810 | AARI_12650 | Putative dolichyl-phosphate-mannose-protein mannosyltransferase; Identified by match to protein family PF02366. Transfers mannosyl residues to the hydroxy of serine or threonine residues, producing cell-wall mannoproteins. | Putative Sua5 family translation factor; Belongs to the SUA5 family. | 0.566 |
AARI_12650 | AARI_00040 | AARI_12650 | AARI_00040 | Putative Sua5 family translation factor; Belongs to the SUA5 family. | Conserved hypothetical protein; Match to protein family PF05258. This family contains several actinomycete proteins of unknown function. | 0.503 |
AARI_12650 | AARI_07810 | AARI_12650 | AARI_07810 | Putative Sua5 family translation factor; Belongs to the SUA5 family. | Putative dolichyl-phosphate-mannose-protein mannosyltransferase; Identified by match to protein family PF02366. Transfers mannosyl residues to the hydroxy of serine or threonine residues, producing cell-wall mannoproteins. | 0.566 |
AARI_12650 | AARI_12660 | AARI_12650 | AARI_12660 | Putative Sua5 family translation factor; Belongs to the SUA5 family. | Putative phospho-N-acetylmuramoyl-pentapeptide-transferase; Match to protein family PF00953. Catalyzes the formation of undecaprenyl-pyrophosphoryl-N-acetylmuramoyl-pentapeptide from UDP-MurNAc-pentapeptide and undecaprenyl-phosphate. Involved in peptidoglycan biosynthesis. | 0.827 |
AARI_12650 | atpB | AARI_12650 | AARI_12680 | Putative Sua5 family translation factor; Belongs to the SUA5 family. | H(+)-transporting two-sector ATPase, chain A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | 0.514 |
AARI_12650 | coaE | AARI_12650 | AARI_19270 | Putative Sua5 family translation factor; Belongs to the SUA5 family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.685 |
AARI_12650 | gcp | AARI_12650 | AARI_23020 | Putative Sua5 family translation factor; Belongs to the SUA5 family. | Probable O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.699 |
AARI_12650 | hemK | AARI_12650 | AARI_12640 | Putative Sua5 family translation factor; Belongs to the SUA5 family. | Putative methylase of peptide chain release factors; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.978 |
AARI_12650 | ksgA | AARI_12650 | AARI_07890 | Putative Sua5 family translation factor; Belongs to the SUA5 family. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.538 |
AARI_12650 | prfA | AARI_12650 | AARI_12630 | Putative Sua5 family translation factor; Belongs to the SUA5 family. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.757 |
AARI_12650 | rho | AARI_12650 | AARI_12620 | Putative Sua5 family translation factor; Belongs to the SUA5 family. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.658 |
AARI_12660 | AARI_12650 | AARI_12660 | AARI_12650 | Putative phospho-N-acetylmuramoyl-pentapeptide-transferase; Match to protein family PF00953. Catalyzes the formation of undecaprenyl-pyrophosphoryl-N-acetylmuramoyl-pentapeptide from UDP-MurNAc-pentapeptide and undecaprenyl-phosphate. Involved in peptidoglycan biosynthesis. | Putative Sua5 family translation factor; Belongs to the SUA5 family. | 0.827 |
AARI_12660 | atpB | AARI_12660 | AARI_12680 | Putative phospho-N-acetylmuramoyl-pentapeptide-transferase; Match to protein family PF00953. Catalyzes the formation of undecaprenyl-pyrophosphoryl-N-acetylmuramoyl-pentapeptide from UDP-MurNAc-pentapeptide and undecaprenyl-phosphate. Involved in peptidoglycan biosynthesis. | H(+)-transporting two-sector ATPase, chain A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | 0.508 |
AARI_12660 | hemK | AARI_12660 | AARI_12640 | Putative phospho-N-acetylmuramoyl-pentapeptide-transferase; Match to protein family PF00953. Catalyzes the formation of undecaprenyl-pyrophosphoryl-N-acetylmuramoyl-pentapeptide from UDP-MurNAc-pentapeptide and undecaprenyl-phosphate. Involved in peptidoglycan biosynthesis. | Putative methylase of peptide chain release factors; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.747 |
AARI_12660 | prfA | AARI_12660 | AARI_12630 | Putative phospho-N-acetylmuramoyl-pentapeptide-transferase; Match to protein family PF00953. Catalyzes the formation of undecaprenyl-pyrophosphoryl-N-acetylmuramoyl-pentapeptide from UDP-MurNAc-pentapeptide and undecaprenyl-phosphate. Involved in peptidoglycan biosynthesis. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.742 |
AARI_12660 | rho | AARI_12660 | AARI_12620 | Putative phospho-N-acetylmuramoyl-pentapeptide-transferase; Match to protein family PF00953. Catalyzes the formation of undecaprenyl-pyrophosphoryl-N-acetylmuramoyl-pentapeptide from UDP-MurNAc-pentapeptide and undecaprenyl-phosphate. Involved in peptidoglycan biosynthesis. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.541 |
atpB | AARI_12650 | AARI_12680 | AARI_12650 | H(+)-transporting two-sector ATPase, chain A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | Putative Sua5 family translation factor; Belongs to the SUA5 family. | 0.514 |