STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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crtEbPutative lycopene elongase; Identified by similarity to protein SP:Q93QX2 (Corynebacterium glutamicum). In Corynebacterium glutamicum MJ233C, CrtEb converts lycopene into the acyclic C50 carotenoid flaxuxanthin by the addition of two C5 isoprenoid groups. (287 aa)    
Predicted Functional Partners:
crtYe
Putative C50 carotenoid epsilon cyclase; Identified by similarity to protein SP:Q93QX4 (Corynebacterium glutamicum). In Corynebacterium glutamicum MJ233C, CrtYe and CrtYf encode the proteins of a C50 carotenoid epsilon cyclase, which is involved in C50 carotenoid biosynthesis. It catalyzes the formation of flavuxanthin from lycopene.
 
  
 0.989
crtYf
Putative C50 carotenoid epsilon cyclase; Identified by similarity to protein SP:Q93QX3 (Corynebacterium glutamicum). In Corynebacterium glutamicum MJ233C, CrtYe and CrtYf encode the proteins of a C50 carotenoid epsilon cyclase, which is involved in C50 carotenoid biosynthesis. It catalyzes the formation of flavuxanthin from lycopene.
 
   
 0.987
crtB
Phytoene synthase; Identified by similarity to protein SP:Q93QX6 (Corynebacterium glutamicum), match to protein family PF00494. Phytoene synthase catalyzes the conversion of two molecules of geranylgeranyl diphosphate (GGPP) into phytoene. It is the second step in the biosynthesis of carotenoids from isopentenyl diphosphate. It is found in all organisms that synthesize carotenoids: plants and photosynthetic bacteria as well as some non- photosynthetic bacteria and fungi.
 
  
 0.986
idi
Isopentenyl-diphosphate Delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
 
 
 0.984
crtI
Putative phytoene desaturase; Identified by similarity to protein SP:Q93QX5 (Corynebacterium glutamicum), match to protein family TIGR02734. Involved in carotenoid biosynthesis. Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (CrtP and CrtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI.
 
  
 0.982
crtE
Farnesyltranstransferase; Identified by similarity to protein SP:Q9KK76 (Brevibacterium linens). A variety of isoprenoid compounds are synthesized by various organisms. In bacteria this pathway leads to the synthesis of isopentenyl tRNA, isoprenoid quinones, and sugar carrier lipids. Farnesyltranstransferase catalyzes the sequential addition of the three molecules of isopentenyl pyrophosphate onto dimethylallyl pyrophosphate to form geranylgeranyl pyrophosphate; Belongs to the FPP/GGPP synthase family.
 
 
 0.969
crtE-2
Putative farnesyltranstransferase; Identified by similarity to protein SP:Q9KK76 (Brevibacterium linens). A variety of isoprenoid compounds are synthesized by various organisms. In bacteria this pathway leads to the synthesis of isopentenyl tRNA, isoprenoid quinones, and sugar carrier lipids. Farnesyltranstransferase catalyzes the sequential addition of the three molecules of isopentenyl pyrophosphate onto dimethylallyl pyrophosphate to form geranylgeranyl pyrophosphate; Belongs to the FPP/GGPP synthase family.
  
 
 0.810
AARI_13700
Putative MarR-family transcriptional regulator; Identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds.
       0.773
AARI_13690
Conserved hypothetical membrane protein; 8 transmembrane helices predicted by TMHMM2.0.
 
     0.729
AARI_13680
Identified by match to protein family PF01370: NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.
 
   
 0.694
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
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